Chokepoint Reaction Finder

Include reactions found in human
Exclude reactions found in human

Include reactions catalyzed by more than one enzyme
Exclude reactions catalyzed by more than one enzyme

Include all reactions
Limit to reactions found in multiple pathways

Definition: A chokepoint reaction is a reaction that either uniquely consumes a specific reactant or uniquely produces a specific product in a metabolic network. The metabolite in question must be balanced by a producing or consuming reaction (in other words, the metabolite must not be a dead-end).

The definition of a chokepoint used here was derived from: Genome Research 14:917 (2004) "Computational analysis of Plasmodium falciparum metabolism: Organizing genomic information to facilitate drug discovery". [Pubmed].

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