Pathway Listing for Homo sapiens Sorted by Pathway Score

Overview

This page presents some of the evidence used to determine which pathways are present in Homo sapiens. For each pathway, we show

• A diagram (the pathway evidence glyph) summarizing the presence of enzymes for each reaction in the pathway
• The normalized pathway score computed for the pathway
• The total number of reactions in the pathway
• The number of pathway reactions which an enzyme is present in Homo sapiens
• The number of those reactions that appear in other pathways in Homo sapiens (and hence are not unique to the particular pathway)
• The number of reactions designated in MetaCyc as key indicators for the presence of this pathway, for which enzymes are present in Homo sapiens
• Whether this organism is within the taxonomic groups (if any) designated in MetaCyc as the taxonomic range of this pathway

Key to Pathway Evidence Glyph Edge Colors

	Enzyme present. An enzyme for this reaction has been identified in this organism
	Enzyme absent. An enzyme for this reaction has not been identified in this organism
	Unique reaction. This reaction is unique to this pathway in the MetaCyc database
	Enzyme present by hole filler. An enzyme for this reaction has been identified in this organism by the Pathway Hole Filler
	Orphan reaction. No sequenced enzyme from any domain of life is known for this reaction
	Key reaction. The reaction has been designated a key reaction of this pathway
	Spontaneous/other. Used for spontaneous reactions, and for lines that do not denote reactions (e.g., denoting repetition in polymerization pathways)

Pathway Summary Statistics

Fraction of genes devoted to metabolism	3251 of 20979 (15%)
Base pathways	367
Total reactions in the base pathways	1803
Base pathway reactions that are pathway holes	403 (22%)
Base pathway reactions that are not pathway holes	1400 (78%)

Pathways Sorted by Pathway Score

Pathway score is a number between 0 and 1 inclusive that indicates the likelihood that a pathway is present; a higher number indiciates a higher likelihood. The pathway score is not a probability. Pathway scores are computed at pathway prediction time and are not updated later, such as due to editing of a pathway.

A pathway might have no pathway score if its presence was inferred by a curator, or if it is a super-pathway (super-pathways are not scored, and are not included in this page).

Pathways with a score less than the prediction threshold (default=0.15) are typically not predicted as present. An exception to this rule is a case where MetaCyc contains experimental evidence that the pathway exists in the exact organism for which pathway inference was performed, in which case the pathway will be imported from MetaCyc no matter its score.

Pathway	Pathway Glyph	Pathway Score	Total Rxns	Rxns Present in Homo sapiens	Rxns Present in Other Pwys	Other Pwys	Key Rxns Present	In Taxonomic Range?	Links
heme biosynthesis from uroporphyrinogen-III I		na	4	4	0	(none)	1 of 1	yes
glycosaminoglycan-protein linkage region biosynthesis		na	4	4	0	(none)	0 of 0	yes
leukotriene biosynthesis		na	6	6	0	(none)	0 of 0	yes
glutathione-peroxide redox reactions		na	3	3	1	reactive oxygen species degradation	0 of 0	yes
di-homo-gamma-linolenate metabolites biosynthesis		na	16	1	0	(none)	0 of 0	yes
fructose 2,6-bisphosphate biosynthesis		na	2	2	0	(none)	0 of 0	yes
PRPP biosynthesis		na	1	1	0	(none)	0 of 0	yes
thyronamine and iodothyronamine metabolism		na	12	8	0	(none)	0 of 0	yes
acetone degradation I (to methylglyoxal)		na	3	1	0	(none)	0 of 0	yes
4-hydroxybenzoate biosynthesis		na	5	1	0	(none)	0 of 0	yes
stearate biosynthesis		na	6	5	0	(none)	1 of 1	yes
CDP-diacylglycerol biosynthesis		na	4	3	0	(none)	0 of 0	yes
estradiol biosynthesis II		na	3	3	0	(none)	0 of 0	yes
11-oxyandrogens biosynthesis		na	20	19	0	(none)	0 of 0	yes
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis		na	4	4	0	(none)	1 of 1	yes
aerobic respiration I (cytochrome c)		na	4	4	0	(none)	0 of 0	yes
chondroitin sulfate degradation (metazoa)		na	1	1	0	(none)	0 of 0	yes
pentose phosphate pathway (non-oxidative branch)		na	5	5	0	(none)	1 of 1	yes
glycine/serine biosynthesis		na	1	1	0	(none)	0 of 0	yes
noradrenaline and adrenaline degradation		na	13	12	0	(none)	3 of 4	yes
heparan sulfate biosynthesis		na	12	12	0	(none)	0 of 0	yes
L-alanine biosynthesis		na	1	1	0	(none)	0 of 0	yes
acetone degradation III (to propane-1,2-diol)		na	2	2	0	(none)	0 of 0	yes
Rapoport-Luebering glycolytic shunt		na	3	3	0	(none)	0 of 0	yes
mucin core 3 and core 4 O-glycosylation		na	3	2	0	(none)	0 of 0	yes
cobalamin salvage (eukaryotic)		na	8	7	0	(none)	0 of 0	yes
peptido-conjugates in tissue regeneration biosynthesis		na	17	16	0	(none)	0 of 0	yes
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)		na	5	5	0	(none)	1 of 1	NO
phosphatidylcholine biosynthesis		na	3	3	0	(none)	0 of 0	yes
pyrimidine ribonucleosides degradation		na	2	2	0	(none)	1 of 1	yes
icosapentaenoate metabolites biosynthesis		na	35	4	0	(none)	0 of 0	yes
dTMP de novo biosynthesis (mitochondrial)		na	3	3	0	(none)	0 of 0	yes
D-galactose degradation V (Leloir pathway)		na	5	5	0	(none)	0 of 0	yes
protein ubiquitination		na	9	9	0	(none)	0 of 0	yes
L-proline degradation		na	3	2	0	(none)	1 of 1	yes
UMP biosynthesis		na	6	6	0	(none)	1 of 1	yes
CMP-N-acetylneuraminate biosynthesis I (eukaryotes)		na	5	5	0	(none)	3 of 3	yes
human milk oligisaccharides biosynthesis		na	19	17	0	(none)	0 of 0	yes
creatine biosynthesis		na	2	2	0	(none)	2 of 2	yes
heme degradation I		na	6	6	0	(none)	0 of 0	yes
thiamine salvage III		na	1	1	0	(none)	0 of 0	yes
NAD phosphorylation and transhydrogenation		na	2	2	0	(none)	0 of 0	yes
N1-methyl-N3-aminocarboxypropyl-pseudouridine-modified rRNA biosynthesis		na	3	3	0	(none)	0 of 0	yes
globo-series glycosphingolipids biosynthesis		na	8	8	0	(none)	0 of 0	yes
carnosine biosynthesis		na	1	1	0	(none)	0 of 0	yes
phosphatidylethanolamine biosynthesis II		na	4	3	0	(none)	1 of 1	yes
glycogenolysis		na	6	5	0	(none)	0 of 0	yes
adenine and adenosine salvage VI		na	1	1	0	(none)	0 of 0	yes
androgen biosynthesis		na	6	6	0	(none)	0 of 0	yes
triacylglycerol degradation		na	3	3	0	(none)	1 of 1	yes
ascorbate recycling (cytosolic)		na	6	1	0	(none)	1 of 2	yes
trehalose degradation		na	2	2	0	(none)	1 of 1	NO
ketogenesis		na	5	5	0	(none)	0 of 0	yes
phenylethylamine degradation I		na	2	2	0	(none)	1 of 1	yes
aspirin triggered resolvin E biosynthesis		na	6	4	0	(none)	0 of 0	yes
TCA cycle		na	10	10	0	(none)	2 of 2	yes
purine ribonucleosides degradation to ribose-1-phosphate		na	6	6	0	(none)	0 of 0	yes
lanosterol biosynthesis		na	1	1	0	(none)	0 of 0	yes
L-asparagine degradation I		na	1	1	0	(none)	0 of 0	yes
complex N-linked glycan biosynthesis (vertebrates)		na	10	10	0	(none)	0 of 0	yes
lipoate salvage		na	na	na	0	(none)	0 of 0	NO
fatty acid beta-oxidation (peroxisome)		na	7	7	0	(none)	1 of 1	yes
spermine and spermidine degradation I		na	5	5	0	(none)	2 of 2	yes
alpha-linolenate metabolites biosynthesis		na	na	na	0	(none)	0 of 0	yes
2'-deoxy-alpha-D-ribose 1-phosphate degradation		na	3	3	0	(none)	0 of 0	yes
epoxysqualene biosynthesis		na	3	3	0	(none)	0 of 0	yes
acyl-CoA hydrolysis		na	1	1	0	(none)	0 of 0	yes
hydrogen sulfide biosynthesis II (mammalian)		na	6	6	0	(none)	0 of 0	yes
purine deoxyribonucleosides salvage		na	6	6	0	(none)	0 of 0	yes
thio-molybdenum cofactor biosynthesis		na	1	1	0	(none)	0 of 0	yes
5-aminoimidazole ribonucleotide biosynthesis		na	5	5	0	(none)	0 of 0	yes
L-tyrosine degradation		na	5	5	0	(none)	0 of 0	yes
D-myo-inositol (1,3,4)-trisphosphate biosynthesis		na	3	3	0	(none)	0 of 0	yes
guanine and guanosine salvage		na	2	2	0	(none)	0 of 0	yes
mRNA capping I		na	3	3	0	(none)	0 of 0	yes
sorbitol degradation I		na	3	1	0	(none)	0 of 0	yes
fatty acid alpha-oxidation III		na	7	6	0	(none)	1 of 1	yes
ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide		na	11	11	2	terminal O-glycans residues modification (via type 2 precursor disaccharide)	0 of 0	yes
spermidine biosynthesis		na	2	2	0	(none)	0 of 0	yes
chondroitin sulfate biosynthesis		na	4	4	0	(none)	0 of 0	yes
trans, trans-farnesyl diphosphate biosynthesis		na	2	2	0	(none)	1 of 1	yes
ethanol degradation II		na	3	3	0	(none)	1 of 1	yes
D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis		na	4	4	0	(none)	1 of 1	yes
cytochrome c biogenesis		na	1	1	0	(none)	0 of 0	yes
nicotine degradation V		na	18	8	0	(none)	0 of 0	yes
protein O-[N-acetyl]-glucosylation		na	2	2	0	(none)	0 of 0	yes
ultra-long-chain fatty acid biosynthesis		na	20	20	0	(none)	0 of 0	yes
L-alanine degradation		na	1	1	0	(none)	0 of 0	yes
2-arachidonoylglycerol biosynthesis		na	7	6	0	(none)	0 of 0	yes
pentose phosphate pathway (oxidative branch)		na	3	3	0	(none)	0 of 0	yes
palmitate biosynthesis (cytoplasm)		na	31	1	0	(none)	0 of 0	yes
adenine and adenosine salvage I		na	2	2	0	(none)	0 of 0	yes
CMP-2-keto-3-deoxy-D-glycero-D-galacto-nononate biosynthesis		na	4	1	0	(none)	0 of 1	yes
bile acid biosynthesis, neutral pathway		na	29	19	0	(none)	1 of 1	yes
UDP-alpha-D-glucose biosynthesis I		na	2	2	0	(none)	0 of 0	yes
tRNA-uridine 2-thiolation (mammalian mitochondria)		na	4	4	0	(none)	0 of 0	yes
thyroid hormone metabolism I (via deiodination)		na	12	9	0	(none)	2 of 2	yes
tRNA splicing II		na	2	2	0	(none)	1 of 1	yes
L-tyrosine biosynthesis		na	1	1	0	(none)	0 of 0	yes
ornithine de novo biosynthesis		na	3	3	0	(none)	0 of 0	yes
dopamine degradation		na	5	5	0	(none)	0 of 0	yes
formaldehyde oxidation II (glutathione-dependent)		na	3	2	0	(none)	1 of 1	yes
D-myo-inositol (1,4,5)-trisphosphate degradation		na	3	3	0	(none)	0 of 0	yes
sulfide oxidation IV (metazoa)		na	5	4	0	(none)	0 of 0	yes
menaquinol-4 biosynthesis II		na	3	1	0	(none)	0 of 0	yes
spermine biosynthesis		na	2	2	0	(none)	1 of 1	yes
arachidonate metabolites biosynthesis		na	74	32	0	(none)	0 of 0	yes
adenosine ribonucleotides de novo biosynthesis		na	3	3	0	(none)	0 of 0	yes
methylglyoxal degradation VI		na	4	1	0	(none)	0 of 0	yes
arsenic detoxification (mammals)		na	17	8	0	(none)	1 of 3	yes
flavin biosynthesis		na	2	2	0	(none)	0 of 0	yes
melatonin degradation II		na	4	1	0	(none)	0 of 1	yes
L-lysine degradation (saccharopine pathway)		na	5	5	0	(none)	0 of 0	yes
L-aspartate degradation I		na	1	1	0	(none)	0 of 0	yes
GDP-glucose biosynthesis II		na	3	3	0	(none)	0 of 0	yes
GDP-L-fucose biosynthesis I (from GDP-D-mannose)		na	3	3	0	(none)	2 of 2	yes
oxidized GTP and dGTP detoxification		na	4	1	0	(none)	0 of 0	yes
phosphatidylserine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
linoleate metabolites biosynthesis		na	14	3	0	(none)	0 of 0	yes
methylglyoxal degradation I		na	3	2	0	(none)	1 of 2	yes
tetrapyrrole biosynthesis		na	4	4	0	(none)	0 of 0	yes
NAD salvage		na	2	2	0	(none)	1 of 1	yes
morphine biosynthesis		na	na	na	0	(none)	0 of 0	yes
maresin biosynthesis		na	5	3	0	(none)	0 of 0	yes
ubiquinol-10 biosynthesis (late decarboxylation)		na	10	8	0	(none)	0 of 0	yes
citrulline-nitric oxide cycle		na	3	3	0	(none)	0 of 0	yes
molybdopterin biosynthesis		na	6	5	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides de novo biosynthesis		na	9	9	0	(none)	1 of 1	yes
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate		na	2	2	0	(none)	0 of 0	yes
acyl carrier protein activation		na	1	1	0	(none)	0 of 0	yes
fatty acid beta-oxidation		na	7	5	0	(none)	0 of 0	yes
lacto-series glycosphingolipids biosynthesis		na	7	7	0	(none)	0 of 0	yes
phospholipases		na	5	5	0	(none)	0 of 0	yes
(S)-reticuline biosynthesis		na	7	1	0	(none)	0 of 0	yes
Arg/N-end rule pathway (eukaryotic)		na	14	11	0	(none)	0 of 0	yes
L-glutamate biosynthesis		na	1	1	1	GABA shunt	0 of 0	yes
L-carnitine biosynthesis		na	4	4	0	(none)	1 of 1	yes
glutathione-mediated detoxification I		na	8	5	0	(none)	0 of 0	yes
taurine biosynthesis II		na	4	3	0	(none)	0 of 0	yes
myo-inositol biosynthesis		na	2	2	0	(none)	1 of 1	yes
blood coagulation - tissue factor pathway		na	11	8	0	(none)	0 of 0	yes
ethanol degradation IV		na	3	3	0	(none)	1 of 1	yes
glutamine biosynthesis		na	1	1	0	(none)	0 of 0	yes
protein NEDDylation		na	3	3	0	(none)	0 of 0	yes
NAD salvage pathway IV (from nicotinamide riboside)		na	2	2	0	(none)	0 of 0	yes
neolacto-series glycosphingolipids biosynthesis		na	12	12	0	(none)	0 of 0	yes
sucrose degradation		na	5	5	0	(none)	0 of 0	yes
L-proline biosynthesis		na	4	3	0	(none)	0 of 0	yes
trans-4-hydroxy-L-proline degradation		na	5	4	0	(none)	0 of 0	yes
anandamide biosynthesis I		na	12	9	0	(none)	3 of 3	yes
serotonin and melatonin biosynthesis		na	4	4	0	(none)	0 of 0	yes
protein O-mannosylation II (mammals, core M1 and core M2)		na	5	4	0	(none)	0 of 0	yes
L-leucine degradation		na	6	6	0	(none)	1 of 1	yes
L-dopa and L-dopachrome biosynthesis		na	3	1	0	(none)	0 of 0	yes
tetrahydropteridine recycling		na	2	2	0	(none)	0 of 0	yes
thioredoxin pathway		na	2	1	0	(none)	0 of 0	yes
L-cysteine biosynthesis III (from L-homocysteine)		na	2	2	0	(none)	0 of 0	yes
vitamin D3 biosynthesis		na	4	2	0	(none)	1 of 1	yes
inositol diphosphates biosynthesis		na	9	9	0	(none)	0 of 0	yes
glycine betaine degradation II (mammalian)		na	4	3	0	(none)	0 of 0	yes
serotonin degradation		na	7	6	0	(none)	1 of 1	yes
resolvin D biosynthesis		na	11	7	0	(none)	0 of 0	yes
adenosine deoxyribonucleotides de novo biosynthesis		na	2	2	0	(none)	0 of 0	yes
anthranilate degradation IV (aerobic)		na	na	na	0	(none)	0 of 0	NO
enediyne-induced DNA damage		na	na	na	0	(none)	0 of 0	yes
sphingomyelin metabolism		na	3	3	3	sphingolipid biosynthesis (mammals)	0 of 0	yes
glycine cleavage		na	3	3	0	(none)	1 of 1	yes
folate transformations I		na	12	9	0	(none)	0 of 0	yes
UTP and CTP dephosphorylation I		na	7	7	0	(none)	0 of 0	yes
4-hydroxy-2-nonenal detoxification		na	4	4	0	(none)	0 of 0	yes
docosahexaenoate biosynthesis III (6-desaturase, mammals)		na	14	7	0	(none)	0 of 0	yes
L-lysine degradation (pipecolate pathway)		na	9	7	0	(none)	0 of 0	yes
sulfite oxidation		na	1	1	0	(none)	0 of 0	yes
alpha-tocopherol degradation		na	3	1	0	(none)	1 of 1	yes
alpha-dystroglycan glycosylation		na	7	7	0	(none)	0 of 0	yes
UDP-N-acetyl-D-galactosamine biosynthesis II		na	7	7	0	(none)	1 of 1	NO
tRNA charging		na	21	20	0	(none)	0 of 0	yes
catecholamine biosynthesis		na	4	4	0	(none)	0 of 0	yes
anandamide biosynthesis II		na	8	3	0	(none)	0 of 0	yes
erythritol biosynthesis II		na	2	1	0	(none)	0 of 0	yes
5-oxo-L-proline metabolism		na	6	4	1	γ-glutamyl cycle	0 of 0	yes
protein O-mannosylation III (mammals, core M3)		na	5	5	0	(none)	0 of 0	yes
adenine and adenosine salvage III		na	4	4	0	(none)	2 of 2	yes
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA		na	5	3	0	(none)	0 of 0	yes
docosahexaenoate biosynthesis IV (4-desaturase, mammals)		na	6	3	0	(none)	1 of 1	yes
N-acetylglucosamine degradation I		na	2	2	0	(none)	0 of 0	yes
guanosine ribonucleotides de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
ATP biosynthesis		na	1	1	0	(none)	0 of 0	yes
L-histidine degradation		na	6	6	0	(none)	0 of 0	yes
nicotine degradation IV		na	16	5	0	(none)	0 of 0	yes
retinoate biosynthesis I		na	4	4	0	(none)	0 of 0	yes
ceramide de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
aspirin triggered resolvin D biosynthesis		na	10	5	0	(none)	0 of 0	yes
choline degradation		na	2	2	0	(none)	0 of 0	yes
L-dopa degradation		na	4	1	0	(none)	1 of 2	yes
progesterone biosynthesis		na	2	2	0	(none)	0 of 0	yes
S-adenosyl-L-methionine biosynthesis		na	1	1	0	(none)	0 of 0	NO
retinoate biosynthesis II		na	3	3	0	(none)	0 of 0	yes
L-serine degradation		na	3	1	0	(none)	0 of 0	yes
icosapentaenoate biosynthesis II (6-desaturase, mammals)		na	7	4	0	(none)	0 of 0	yes
acylceramide biosynthesis and processing		na	8	7	0	(none)	0 of 0	yes
BMP Signalling Pathway		na	17	2	0	(none)	0 of 0	yes
guanosine deoxyribonucleotides de novo biosynthesis		na	2	2	0	(none)	0 of 0	yes
dermatan sulfate biosynthesis		na	6	4	0	(none)	0 of 0	yes
D-mannose degradation		na	1	1	0	(none)	0 of 0	yes
plasmalogen biosynthesis		na	16	15	0	(none)	1 of 1	yes
retinol biosynthesis		na	7	7	0	(none)	0 of 0	yes
carbon disulfide oxidation III (metazoa)		na	5	1	0	(none)	0 of 0	yes
protectin biosynthesis		na	6	4	0	(none)	0 of 0	yes
cardenolide biosynthesis		na	10	1	0	(none)	0 of 0	NO
dolichol and dolichyl phosphate biosynthesis		na	6	5	0	(none)	1 of 1	yes
4-aminobutanoate degradation I		na	2	2	2	GABA shunt	0 of 0	yes
glycogen biosynthesis		na	4	4	0	(none)	1 of 1	yes
pyruvate fermentation to (S)-lactate		na	1	1	0	(none)	0 of 0	yes
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation		na	7	6	0	(none)	1 of 1	yes
procollagen hydroxylation and glycosylation		na	6	5	0	(none)	0 of 0	yes
homocarnosine biosynthesis		na	1	1	0	(none)	0 of 0	yes
the visual cycle I (vertebrates)		na	12	8	0	(none)	0 of 0	yes
putrescine biosynthesis I		na	2	2	0	(none)	0 of 0	yes
GDP-L-fucose biosynthesis II (from L-fucose)		na	2	2	0	(none)	0 of 0	yes
cardiolipin biosynthesis		na	3	3	0	(none)	0 of 0	yes
acetate conversion to acetyl-CoA		na	1	1	0	(none)	0 of 0	yes
2-oxoglutarate decarboxylation to succinyl-CoA		na	3	3	0	(none)	1 of 1	yes
glutaminyl-tRNAgln biosynthesis via transamidation		na	4	3	0	(none)	0 of 0	yes
L-aspartate biosynthesis		na	1	1	0	(none)	0 of 0	yes
propanoyl CoA degradation I		na	3	3	0	(none)	0 of 0	yes
glutaryl-CoA degradation		na	5	5	0	(none)	0 of 0	yes
beta-alanine degradation		na	2	2	0	(none)	0 of 0	yes
phosphatidylserine biosynthesis II		na	1	1	0	(none)	0 of 0	yes
putrescine degradation III		na	4	3	0	(none)	0 of 0	yes
lipoxin biosynthesis		na	11	8	0	(none)	0 of 0	yes
palmitoyl ethanolamide biosynthesis		na	6	2	0	(none)	1 of 1	yes
itaconate biosynthesis I		na	2	1	0	(none)	1 of 1	yes
dermatan sulfate degradation (metazoa)		na	na	na	0	(none)	0 of 0	yes
anandamide lipoxygenation		na	6	3	0	(none)	0 of 0	yes
L-methionine salvage from L-homocysteine		na	3	3	0	(none)	0 of 0	yes
tRNA-uridine 2-thiolation (cytoplasmic)		na	8	7	0	(none)	0 of 0	yes
biotin-carboxyl carrier protein assembly		na	4	3	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotide phosphorylation		na	4	4	0	(none)	0 of 0	yes
arachidonate biosynthesis IV (8-detaturase)		na	7	2	0	(none)	0 of 1	yes
glycolysis		na	10	10	0	(none)	0 of 0	yes
fatty acid alpha-oxidation		na	6	5	0	(none)	2 of 2	yes
L-isoleucine degradation		na	6	6	0	(none)	0 of 0	yes
purine deoxyribonucleosides degradation		na	3	3	0	(none)	0 of 0	yes
anandamide degradation		na	1	1	0	(none)	0 of 0	yes
oleate biosynthesis		na	2	2	0	(none)	0 of 0	yes
sulfate activation for sulfonation		na	2	2	0	(none)	0 of 0	yes
icosapentaenoate biosynthesis III (8-desaturase, mammals)		na	7	4	0	(none)	1 of 1	yes
2-methyl-branched fatty acid beta-oxidation		na	14	8	0	(none)	0 of 0	yes
L-methionine degradation		na	3	2	0	(none)	0 of 0	yes
diacylglycerol and triacylglycerol biosynthesis		na	7	4	0	(none)	0 of 0	yes
L-cysteine degradation I		na	3	2	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation (animals and fungi, cytoplasm)		na	3	3	0	(none)	0 of 0	yes
L-glutamate degradation (via 4-aminobutanoate)		na	1	1	1	GABA shunt	0 of 0	yes
ganglio-series glycosphingolipids biosynthesis		na	22	22	0	(none)	0 of 0	yes
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde		na	5	5	5	L-tryptophan degradation XI (mammalian, via kynurenine)	0 of 0	yes
plasmalogen degradation		na	8	8	0	(none)	0 of 0	yes
malate-aspartate shuttle		na	2	2	0	(none)	0 of 0	yes
mevalonate pathway		na	7	7	0	(none)	2 of 2	yes
histamine biosynthesis		na	1	1	0	(none)	0 of 0	yes
estradiol biosynthesis I (via estrone)		na	4	4	0	(none)	0 of 0	yes
L-asparagine biosynthesis		na	1	1	0	(none)	0 of 0	yes
D-myo-inositol-5-phosphate metabolism		na	4	4	0	(none)	0 of 0	yes
phosphatidylethanolamine biosynthesis III		na	1	1	0	(none)	0 of 0	yes
protein N-glycosylation initial phase (eukaryotic)		na	19	16	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides biosynthesis from CTP		na	8	8	0	(none)	1 of 1	yes
diphthamide biosynthesis		na	3	2	0	(none)	0 of 0	NO
molybdenum cofactor biosynthesis		na	3	2	0	(none)	1 of 1	yes
UTP and CTP de novo biosynthesis		na	3	3	0	(none)	0 of 0	yes
docosahexaenoate metabolites biosynthesis		na	31	16	0	(none)	0 of 0	yes
myristate biosynthesis (mitochondria)		na	25	25	0	(none)	0 of 0	yes
ophthalmate biosynthesis		na	3	3	0	(none)	0 of 0	yes
protein S-nitrosylation and denitrosylation		na	5	1	0	(none)	0 of 0	yes
S-methyl-5'-thioadenosine degradation		na	1	1	0	(none)	0 of 0	yes
NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde		na	4	3	0	(none)	0 of 0	yes
L-cysteine degradation III		na	2	2	0	(none)	0 of 0	yes
ketolysis		na	3	3	0	(none)	0 of 0	yes
sphingosine and sphingosine-1-phosphate metabolism		na	10	6	0	(none)	0 of 0	yes
inosine-5'-phosphate biosynthesis		na	5	5	0	(none)	1 of 1	yes
L-phenylalanine degradation I (aerobic)		na	1	1	0	(none)	0 of 0	yes
coenzyme A biosynthesis II (eukaryotic)		na	4	4	0	(none)	1 of 1	yes
mineralocorticoid biosynthesis		na	5	4	0	(none)	0 of 0	yes
L-selenocysteine biosynthesis		na	4	4	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation (mitochondria)		na	4	3	0	(none)	1 of 1	yes
7-(3-amino-3-carboxypropyl)-wyosine biosynthesis		na	4	3	0	(none)	0 of 0	NO
creatine-phosphate biosynthesis		na	1	1	0	(none)	0 of 0	yes
melatonin degradation I		na	5	5	0	(none)	2 of 2	yes
thiosulfate disproportionation IV (rhodanese)		na	1	1	0	(none)	0 of 0	yes
UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)		na	1	1	0	(none)	0 of 0	yes
glycine biosynthesis		na	1	1	0	(none)	0 of 0	yes
mitochondrial L-carnitine shuttle		na	3	2	0	(none)	1 of 1	yes
pyrimidine deoxyribonucleosides salvage		na	5	5	0	(none)	0 of 0	yes
arachidonate biosynthesis V (8-detaturase, mammals)		na	6	4	1	arachidonate biosynthesis III (6-desaturase, mammals)	2 of 2	yes
D-myo-inositol (1,4,5)-trisphosphate biosynthesis		na	5	5	0	(none)	0 of 0	yes
putrescine biosynthesis III		na	2	2	0	(none)	0 of 0	yes
C20 prostanoid biosynthesis		na	17	11	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleosides degradation		na	3	3	0	(none)	0 of 0	yes
CMP phosphorylation		na	2	2	0	(none)	0 of 0	yes
ethanol degradation III		na	3	3	0	(none)	1 of 1	yes
L-tryptophan degradation via tryptamine		na	4	4	0	(none)	3 of 3	yes
L-glutamine degradation		na	1	1	0	(none)	0 of 0	yes
superoxide radicals degradation		na	2	2	2	reactive oxygen species degradation	0 of 0	yes
glucocorticoid biosynthesis		na	4	3	0	(none)	0 of 0	yes
lactose degradation III		na	1	1	0	(none)	0 of 0	yes
tetrahydrobiopterin de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
adenosine nucleotides degradation		na	5	5	0	(none)	1 of 1	yes
NADH repair		na	4	4	0	(none)	1 of 1	yes
acetyl-CoA biosynthesis from citrate		na	1	1	0	(none)	0 of 0	yes
L-serine biosynthesis		na	3	3	0	(none)	0 of 0	yes
phytol degradation		na	4	2	0	(none)	1 of 1	yes
protein N-glycosylation processing phase (mammalian)		na	20	19	0	(none)	0 of 0	yes
pregnenolone biosynthesis		na	3	3	0	(none)	0 of 0	yes
queuosine biosynthesis II (queuine salvage)		na	1	1	0	(none)	0 of 0	yes
lipoate biosynthesis and incorporation		na	3	3	0	(none)	0 of 0	yes
[2Fe-2S] iron-sulfur cluster biosynthesis		na	10	1	0	(none)	0 of 0	yes
zymosterol biosynthesis		na	8	8	5	cholesterol biosynthesis I	0 of 0	yes
MAP kinase cascade		na	4	2	0	(none)	0 of 0	yes
fatty acid beta-oxidation (unsaturated, odd number)		na	1	1	0	(none)	0 of 0	yes
melatonin degradation III		na	2	1	0	(none)	0 of 0	yes
3-phosphoinositide biosynthesis		na	8	8	0	(none)	0 of 0	yes
thyroid hormone metabolism II (via conjugation and/or degradation)		na	15	11	0	(none)	6 of 6	yes
allopregnanolone biosynthesis		na	2	2	0	(none)	0 of 0	yes
geranylgeranyl diphosphate biosynthesis		na	1	1	0	(none)	0 of 0	yes
uracil degradation I (reductive)		na	3	3	0	(none)	0 of 0	yes
15-epi-lipoxin biosynthesis		na	5	3	0	(none)	0 of 0	yes
guanosine nucleotides degradation		na	4	4	0	(none)	0 of 0	yes
chondroitin biosynthesis		na	3	3	0	(none)	0 of 0	yes
taurine biosynthesis I		na	3	3	0	(none)	0 of 0	yes
histamine degradation		na	3	2	0	(none)	1 of 1	yes
inosine 5'-phosphate degradation		na	4	4	0	(none)	0 of 0	yes
glycerol-3-phosphate shuttle		na	2	1	0	(none)	0 of 0	yes
mucin core 1 and core 2 O-glycosylation		na	5	5	0	(none)	0 of 0	yes
glutathione biosynthesis		na	2	2	0	(none)	0 of 0	yes
pyridoxal 5'-phosphate salvage		na	5	5	0	(none)	0 of 0	yes
very long chain fatty acid biosynthesis II		na	16	14	0	(none)	0 of 0	yes
long-chain fatty acid activation		na	1	1	0	(none)	0 of 0	yes
UDP-N-acetyl-D-galactosamine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
2-oxoisovalerate decarboxylation to isobutanoyl-CoA		na	3	3	0	(none)	1 of 1	yes
thyroid hormone biosynthesis		na	6	5	0	(none)	4 of 4	yes
glutathione-glutaredoxin redox reactions		na	2	1	0	(none)	0 of 0	yes
glycerol degradation		na	3	1	0	(none)	0 of 0	yes
protein citrullination		na	1	1	0	(none)	0 of 0	yes
gala-series glycosphingolipids biosynthesis		na	5	4	0	(none)	0 of 0	yes
L-threonine degradation		na	2	2	1	2-oxobutanoate degradation	0 of 0	yes
ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide		na	10	10	0	(none)	0 of 0	yes
urea cycle		na	5	5	0	(none)	2 of 2	yes
UDP-N-acetyl-D-glucosamine biosynthesis II		na	6	6	0	(none)	0 of 0	yes
D-glucuronate degradation		na	5	3	0	(none)	0 of 0	yes
L-valine degradation		na	8	8	0	(none)	0 of 0	yes
eumelanin biosynthesis		na	6	3	0	(none)	0 of 0	yes
gluconeogenesis		na	12	12	0	(none)	0 of 0	yes
thymine degradation		na	3	3	0	(none)	0 of 0	yes
heme a biosynthesis		na	4	3	0	(none)	2 of 2	yes
vitamin K-epoxide cycle		na	4	4	0	(none)	0 of 0	yes
pyruvate decarboxylation to acetyl CoA		na	3	3	0	(none)	1 of 1	yes
gamma-linolenate biosynthesis		na	2	2	0	(none)	1 of 1	yes
bupropion degradation		na	5	1	0	(none)	0 of 0	yes
i antigen and I antigen biosynthesis		na	6	5	5	terminal O-glycans residues modification (via type 2 precursor disaccharide)	0 of 0	yes
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)		na	5	5	0	(none)	1 of 1	yes
pyrimidine ribonucleosides salvage I		na	3	2	0	(none)	1 of 1	yes
GDP-mannose biosynthesis		na	4	4	0	(none)	0 of 0	yes
3-phosphoinositide degradation		na	9	8	0	(none)	0 of 0	yes
folate polyglutamylation		na	5	4	0	(none)	0 of 0	yes
hypusine biosynthesis		na	5	5	0	(none)	0 of 0	yes
valproate beta-oxidation		na	9	5	0	(none)	0 of 0	yes
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)		na	5	4	0	(none)	1 of 1	yes
methylglyoxal degradation III		na	2	2	0	(none)	0 of 0	yes

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Please cite the following article in publications resulting from the use of HumanCyc: Genome Biology 6(1):1-17 2004
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