Pathway Listing for Homo sapiens Sorted by Pathway Score

Overview

This page presents some of the evidence used to determine which pathways are present in Homo sapiens. For each pathway, we show

• A diagram (the pathway evidence glyph) summarizing the presence of enzymes for each reaction in the pathway
• The normalized pathway score computed for the pathway
• The total number of reactions in the pathway
• The number of pathway reactions which an enzyme is present in Homo sapiens
• The number of those reactions that appear in other pathways in Homo sapiens (and hence are not unique to the particular pathway)
• The number of reactions designated in MetaCyc as key indicators for the presence of this pathway, for which enzymes are present in Homo sapiens
• Whether this organism is within the taxonomic groups (if any) designated in MetaCyc as the taxonomic range of this pathway

Key to Pathway Evidence Glyph Edge Colors

	Enzyme present. An enzyme for this reaction has been identified in this organism
	Enzyme absent. An enzyme for this reaction has not been identified in this organism
	Unique reaction. This reaction is unique to this pathway in the MetaCyc database
	Enzyme present by hole filler. An enzyme for this reaction has been identified in this organism by the Pathway Hole Filler
	Orphan reaction. No sequenced enzyme from any domain of life is known for this reaction
	Key reaction. The reaction has been designated a key reaction of this pathway
	Spontaneous/other. Used for spontaneous reactions, and for lines that do not denote reactions (e.g., denoting repetition in polymerization pathways)

Pathway Summary Statistics

Fraction of genes devoted to metabolism	3051 of 59059 (5%)
Base pathways	395
Total reactions in the base pathways	1862
Base pathway reactions that are pathway holes	328 (18%)
Base pathway reactions that are not pathway holes	1534 (82%)

Pathways Sorted by Pathway Score

Pathway score is a number between 0 and 1 inclusive that indicates the likelihood that a pathway is present; a higher number indiciates a higher likelihood. The pathway score is not a probability. Pathway scores are computed at pathway prediction time and are not updated later, such as due to editing of a pathway.

A pathway might have no pathway score if its presence was inferred by a curator, or if it is a super-pathway (super-pathways are not scored, and are not included in this page).

Pathways with a score less than the prediction threshold (default=0.15) are typically not predicted as present. An exception to this rule is a case where MetaCyc contains experimental evidence that the pathway exists in the exact organism for which pathway inference was performed, in which case the pathway will be imported from MetaCyc no matter its score.

Pathway	Pathway Glyph	Pathway Score	Total Rxns	Rxns Present in Homo sapiens	Rxns Present in Other Pwys	Other Pwys	Key Rxns Present	In Taxonomic Range?	Links
dermatan sulfate degradation (metazoa)		0	na	na	0	(none)	0 of 0	yes
BMP Signalling Pathway		na	17	2	0	(none)	0 of 0	yes
glycosylphosphatidylinositol anchor biosynthesis (mammalia)		na	15	13	0	(none)	0 of 0	yes
morphine biosynthesis		0	na	na	0	(none)	0 of 0	yes
ascorbate recycling (cytosolic)		0	6	1	0	(none)	1 of 2	yes
D-galactose degradation V (Leloir pathway)		na	5	5	0	(none)	0 of 0	yes
melatonin degradation II		0	4	1	0	(none)	0 of 1	yes
GDP-glucose biosynthesis II		na	3	3	0	(none)	0 of 0	yes
enediyne-induced DNA damage		0	na	na	0	(none)	0 of 0	yes
folate transformations I		na	12	10	0	(none)	0 of 0	yes
D-mannose degradation		na	1	1	0	(none)	0 of 0	yes
pyridoxal 5'-phosphate salvage		na	5	5	0	(none)	0 of 0	yes
glycosylphosphatidylinositol anchor modification (mammalia)		na	6	5	0	(none)	0 of 0	yes
MAP kinase cascade		na	4	2	0	(none)	0 of 0	yes
glycolysis		na	10	10	0	(none)	0 of 0	yes
alpha-linolenate metabolites biosynthesis		0	na	na	0	(none)	0 of 0	yes
methylglyoxal degradation I		0.0142	3	2	0	(none)	1 of 2	yes
(S)-reticuline biosynthesis		0.0807	7	1	0	(none)	0 of 0	yes
4-hydroxybenzoate biosynthesis		0.0925	5	1	0	(none)	0 of 0	yes
S-adenosyl-L-methionine biosynthesis		0.114	1	1	0	(none)	0 of 0	NO
glycerol degradation I		0.128	3	3	0	(none)	0 of 0	yes
diphthamide biosynthesis		0.128	3	2	0	(none)	0 of 0	NO
thiamine salvage III		0.128	1	1	0	(none)	0 of 0	yes
L-dopa degradation		0.165	4	1	0	(none)	1 of 2	yes
[2Fe-2S] iron-sulfur cluster biosynthesis		0.176	10	1	0	(none)	0 of 0	yes
sorbitol degradation I		0.2	3	2	0	(none)	0 of 0	yes
trehalose degradation II (cytosolic)		0.21	2	2	0	(none)	1 of 1	NO
glycine biosynthesis I		0.227	1	1	0	(none)	0 of 0	yes
L-aspartate degradation I		0.244	1	1	0	(none)	0 of 0	yes
L-citrulline degradation		0.259	3	2	0	(none)	1 of 1	yes
L-malate degradation II		0.263	1	1	0	(none)	0 of 0	yes
long-chain fatty acid activation		0.283	1	1	0	(none)	0 of 0	yes
pyruvate fermentation to (S)-lactate		0.283	1	1	0	(none)	0 of 0	yes
N-acetylglucosamine degradation I		0.302	2	2	0	(none)	0 of 0	yes
linoleate metabolites biosynthesis		0.312	14	3	0	(none)	0 of 0	yes
bupropion degradation		0.352	5	1	0	(none)	0 of 0	yes
beta-alanine degradation		0.353	2	2	0	(none)	0 of 0	yes
diacylglycerol and triacylglycerol biosynthesis		0.372	7	4	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides dephosphorylation		0.388	3	2	0	(none)	0 of 0	yes
formaldehyde oxidation VII (THF pathway)		0.398	4	3	0	(none)	0 of 0	yes
lactose degradation III		0.4	1	1	0	(none)	0 of 0	yes
NAD salvage		0.421	2	2	0	(none)	1 of 1	yes
UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)		0.423	1	1	0	(none)	0 of 0	yes
molybdenum cofactor biosynthesis		0.423	3	2	0	(none)	0 of 1	yes
acetone degradation III (to propane-1,2-diol)		0.423	2	1	0	(none)	0 of 0	yes
methylglyoxal degradation III		0.423	2	1	0	(none)	0 of 0	yes
acetone degradation I (to methylglyoxal)		0.423	3	1	0	(none)	0 of 0	yes
superoxide radicals degradation		0.423	2	2	2	reactive oxygen species degradation	0 of 0	yes
pheomelanin biosynthesis		0.423	8	1	0	(none)	0 of 0	yes
glycerol-3-phosphate shuttle		0.423	2	2	0	(none)	0 of 0	yes
phenylethylamine degradation I		0.424	2	2	0	(none)	1 of 1	yes
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA		0.427	5	3	0	(none)	0 of 0	yes
glycine biosynthesis II		0.429	3	3	0	(none)	0 of 0	yes
nicotine degradation IV		0.436	16	5	0	(none)	0 of 0	yes
thioredoxin pathway (NADPH)		0.44	2	1	0	(none)	0 of 0	yes
thiamine triphosphate metabolism		0.44	2	1	0	(none)	0 of 0	yes
folate polyglutamylation		0.446	5	4	0	(none)	0 of 0	yes
L-methionine degradation I (to L-homocysteine)		0.45	3	2	0	(none)	0 of 0	yes
L-glutamine degradation		0.455	1	1	0	(none)	0 of 0	yes
fatty acid beta-oxidation		0.455	7	5	0	(none)	0 of 0	yes
malate-aspartate shuttle		0.469	2	2	0	(none)	0 of 0	yes
phosphatidylethanolamine biosynthesis II		0.475	4	3	0	(none)	1 of 1	yes
docosahexaenoate metabolites biosynthesis		0.478	31	16	0	(none)	0 of 0	yes
acetate conversion to acetyl-CoA		0.478	1	1	0	(none)	0 of 0	yes
geranylgeranyl diphosphate biosynthesis		0.478	1	1	0	(none)	0 of 0	yes
protectin biosynthesis		0.484	6	4	0	(none)	0 of 0	yes
UDP-alpha-D-glucose biosynthesis		0.487	2	2	0	(none)	0 of 0	yes
L-aspartate biosynthesis		0.488	1	1	0	(none)	0 of 0	yes
L-alanine biosynthesis II		0.503	1	1	0	(none)	0 of 0	yes
L-glutamine biosynthesis I		0.503	1	1	0	(none)	0 of 0	yes
NADP biosynthesis		0.503	1	1	0	(none)	0 of 0	yes
L-alanine degradation		0.503	1	1	0	(none)	0 of 0	yes
D-mannose degradation II		0.518	2	2	0	(none)	0 of 0	yes
adenine and adenosine salvage I		0.526	2	2	0	(none)	0 of 0	yes
L-serine degradation		0.526	3	2	0	(none)	0 of 0	yes
UDP-N-acetyl-D-galactosamine biosynthesis II		0.535	7	7	0	(none)	1 of 1	NO
flavin biosynthesis		0.545	2	2	0	(none)	0 of 0	yes
arachidonate metabolites biosynthesis		0.551	74	34	0	(none)	0 of 0	yes
icosapentaenoate metabolites biosynthesis		0.563	35	12	0	(none)	0 of 0	yes
CDP-diacylglycerol biosynthesis I		0.564	4	3	0	(none)	0 of 0	yes
4-aminobutanoate degradation I		0.585	2	2	2	GABA shunt I	0 of 0	yes
protein S-nitrosylation and denitrosylation		0.587	5	1	0	(none)	0 of 0	yes
carbon disulfide oxidation III (metazoa)		0.587	5	1	0	(none)	0 of 0	yes
representative whole plasma EPA-derived icosanoids		0.587	4	1	0	(none)	0 of 0	yes
menaquinol-4 biosynthesis II		0.587	3	1	0	(none)	0 of 0	yes
representative whole plasma arachidonate-derived icosanoids II		0.593	19	10	0	(none)	0 of 0	yes
aspirin triggered resolvin D biosynthesis		0.606	10	5	0	(none)	0 of 0	yes
maresin biosynthesis		0.61	5	3	0	(none)	0 of 0	yes
glycine cleavage		0.613	3	3	0	(none)	1 of 1	yes
representative whole plasma DHA-derived icosanoids		0.613	12	3	0	(none)	0 of 0	yes
icosapentaenoate biosynthesis II (6-desaturase, mammals)		0.614	7	4	0	(none)	0 of 0	yes
resolvin D biosynthesis		0.624	11	7	0	(none)	0 of 0	yes
dipyrromethane cofactor biosynthesis		0.635	4	3	0	(none)	0 of 0	yes
lipoxin biosynthesis		0.639	11	8	0	(none)	0 of 0	yes
UDP-N-acetyl-D-galactosamine biosynthesis I		0.644	1	1	0	(none)	0 of 0	yes
phosphatidylinositol biosynthesis II (eukaryotes)		0.644	1	1	0	(none)	0 of 0	yes
arsenic detoxification (mammals)		0.647	17	8	0	(none)	1 of 3	yes
methylglyoxal degradation VI		0.652	4	1	0	(none)	0 of 0	yes
palmitoleate biosynthesis IV (fungi and animals)		0.652	2	2	0	(none)	0 of 0	yes
L-cysteine degradation I		0.652	3	2	0	(none)	0 of 0	yes
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate		0.653	2	2	0	(none)	0 of 0	yes
putrescine biosynthesis I		0.667	2	2	0	(none)	0 of 0	yes
putrescine biosynthesis III		0.667	2	2	0	(none)	0 of 0	yes
sulfate activation for sulfonation		0.675	2	2	0	(none)	0 of 0	yes
NAD phosphorylation and transhydrogenation		0.675	2	2	0	(none)	0 of 0	yes
aspirin triggered resolvin E biosynthesis		0.677	6	4	0	(none)	0 of 0	yes
nicotine degradation V		0.681	18	8	0	(none)	0 of 0	yes
guanine and guanosine salvage I		0.686	2	2	0	(none)	0 of 0	yes
docosahexaenoate biosynthesis IV (4-desaturase, mammals)		0.691	6	3	0	(none)	1 of 1	yes
C20 prostanoid biosynthesis		0.696	17	11	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation (mitochondria)		0.702	4	3	0	(none)	1 of 1	yes
choline degradation I		0.706	2	2	0	(none)	0 of 0	yes
mannitol degradation II		0.742	4	3	0	(none)	0 of 0	NO
icosapentaenoate biosynthesis III (8-desaturase, mammals)		0.742	7	4	0	(none)	1 of 1	yes
guanosine deoxyribonucleotides de novo biosynthesis I		0.745	2	2	0	(none)	0 of 0	yes
adenosine deoxyribonucleotides de novo biosynthesis I		0.745	2	2	0	(none)	0 of 0	yes
trans, trans-farnesyl diphosphate biosynthesis		0.791	2	2	0	(none)	1 of 1	yes
Ac/N-end rule pathway		0.791	21	21	0	(none)	0 of 0	yes
2-deoxy-alpha-D-ribose 1-phosphate degradation		0.812	3	3	0	(none)	0 of 0	yes
D-glucuronate degradation		0.813	5	4	0	(none)	0 of 0	yes
sphingosine and sphingosine-1-phosphate metabolism		0.841	10	5	0	(none)	0 of 0	yes
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)		0.843	5	5	0	(none)	1 of 1	NO
docosahexaenoate biosynthesis III (6-desaturase, mammals)		0.846	14	8	0	(none)	0 of 0	yes
acetyl-CoA biosynthesis from citrate		0.846	1	1	0	(none)	0 of 0	yes
L-tyrosine biosynthesis		0.846	1	1	0	(none)	0 of 0	yes
fatty acid beta-oxidation (unsaturated, odd number)		0.846	1	1	0	(none)	0 of 0	yes
trimethylamine N-oxide biosynthesis		0.846	1	1	0	(none)	0 of 0	yes
L-glutamate degradation (via 4-aminobutanoate)		0.846	1	1	1	GABA shunt I	0 of 0	yes
phosphatidylethanolamine biosynthesis III		0.846	1	1	0	(none)	0 of 0	yes
S-methyl-5'-thioadenosine degradation II		0.846	1	1	0	(none)	0 of 0	yes
serine racemization		0.846	1	1	0	(none)	0 of 0	yes
glutathione-glutaredoxin redox reactions		0.846	2	1	0	(none)	0 of 0	yes
L-alanine biosynthesis III		0.846	1	1	0	(none)	0 of 0	yes
acyl carrier protein activation		0.846	1	1	0	(none)	0 of 0	yes
progesterone biosynthesis		0.846	2	2	0	(none)	0 of 0	yes
L-cysteine degradation IV		0.846	1	1	0	(none)	0 of 0	yes
sulfite oxidation IV (sulfite oxidase)		0.846	1	1	0	(none)	0 of 0	yes
L-cysteine biosynthesis III (from L-homocysteine)		0.846	2	2	0	(none)	0 of 0	yes
cytochrome c biogenesis		0.846	1	1	0	(none)	0 of 0	yes
L-glutamate biosynthesis		0.846	1	1	1	GABA shunt I	0 of 0	yes
L-phenylalanine degradation I (aerobic)		0.846	1	1	0	(none)	0 of 0	yes
phosphatidylserine biosynthesis II		0.846	1	1	0	(none)	0 of 0	yes
L-dopa and L-dopachrome biosynthesis		0.846	3	1	0	(none)	0 of 0	yes
taurine biosynthesis II		0.863	4	3	0	(none)	0 of 0	yes
diphthamide biosynthesis II (eukaryotes)		0.863	4	3	0	(none)	0 of 0	yes
anandamide biosynthesis II		0.872	8	5	0	(none)	0 of 0	yes
valproate beta-oxidation		0.876	9	5	0	(none)	0 of 0	yes
L-proline degradation		0.879	3	2	0	(none)	1 of 1	yes
melatonin degradation III		0.88	2	1	0	(none)	0 of 0	yes
erythritol biosynthesis II		0.88	2	1	0	(none)	0 of 0	yes
thio-molybdenum cofactor biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
acyl-CoA hydrolysis		0.88	1	1	0	(none)	0 of 0	yes
L-asparagine degradation I		0.88	1	1	0	(none)	0 of 0	yes
oxidized GTP and dGTP detoxification		0.88	4	1	0	(none)	0 of 0	yes
thiosulfate disproportionation IV (rhodanese)		0.88	1	1	0	(none)	0 of 0	yes
glycine biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
di-homo-gamma-linolenate metabolites biosynthesis		0.88	16	8	0	(none)	0 of 0	yes
alpha-tocopherol degradation		0.953	3	1	0	(none)	1 of 1	yes
7-(3-amino-3-carboxypropyl)-wyosine biosynthesis		0.996	4	4	0	(none)	0 of 0	NO
heme a biosynthesis		1.0	4	3	0	(none)	2 of 2	yes
propanoyl CoA degradation I		1.0	3	3	0	(none)	0 of 0	yes
thyroid hormone metabolism I (via deiodination)		1.0	12	9	0	(none)	2 of 2	yes
triacylglycerol degradation		1.0	3	3	0	(none)	1 of 1	yes
protein O-mannosylation III (mammals, core M3)		1.0	5	5	0	(none)	0 of 0	yes
2-oxoisovalerate decarboxylation to isobutanoyl-CoA		1.0	3	3	0	(none)	1 of 1	yes
L-arginine degradation I (arginase pathway)		1.0	3	3	0	(none)	0 of 0	yes
L-cysteine degradation III		1.0	2	2	0	(none)	0 of 0	yes
pentose phosphate pathway (non-oxidative branch) I		1.0	5	5	0	(none)	1 of 1	yes
3-phosphoinositide degradation		1.0	9	8	0	(none)	0 of 0	yes
chondroitin sulfate biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleosides salvage		1.0	5	5	0	(none)	0 of 0	yes
fatty acid alpha-oxidation		1.0	6	5	0	(none)	2 of 2	yes
bile acid biosynthesis, neutral pathway		1.0	29	21	0	(none)	1 of 1	yes
peptido-conjugates in tissue regeneration biosynthesis		1.0	17	16	0	(none)	0 of 0	yes
arachidonate biosynthesis V (8-detaturase, mammals)		1.0	6	4	1	arachidonate biosynthesis III (6-desaturase, mammals)	2 of 2	yes
3-phosphoinositide biosynthesis		1.0	8	8	0	(none)	0 of 0	yes
dopamine degradation		1.0	5	5	0	(none)	0 of 0	yes
backdoor pathway of androgen biosynthesis		1.0	13	11	0	(none)	0 of 0	yes
L-carnitine biosynthesis		1.0	4	4	0	(none)	1 of 1	yes
acylceramide biosynthesis and processing		1.0	8	7	0	(none)	0 of 0	yes
melatonin degradation I		1.0	5	5	0	(none)	2 of 2	yes
glutaryl-CoA degradation		1.0	5	5	0	(none)	0 of 0	yes
retinoate biosynthesis I		1.0	4	4	0	(none)	0 of 0	yes
catecholamine biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
D-myo-inositol (1,4,5)-trisphosphate degradation		1.0	3	3	0	(none)	0 of 0	yes
putrescine degradation III		1.0	4	3	0	(none)	0 of 0	yes
blood coagulation - tissue factor pathway		1.0	11	8	0	(none)	0 of 0	yes
heme b biosynthesis I (aerobic)		1.0	4	4	0	(none)	1 of 1	yes
cardiolipin biosynthesis		1.0	3	3	2	phosphatidylglycerol biosynthesis II	0 of 0	yes
NADPH repair (eukaryotes)		1.0	4	1	0	(none)	1 of 1	yes
tRNA-uridine 2-thiolation (mammalian mitochondria)		1.0	4	4	0	(none)	0 of 0	yes
palmitate biosynthesis I (type I fatty acid synthase)		1.0	31	2	0	(none)	0 of 0	yes
fatty acid alpha-oxidation III		1.0	7	5	0	(none)	1 of 1	yes
NADH repair		1.0	4	4	0	(none)	1 of 1	yes
aerobic respiration I (cytochrome c)		1.0	4	4	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleosides degradation		1.0	3	3	0	(none)	0 of 0	yes
ethanol degradation III		1.0	3	3	0	(none)	1 of 1	yes
Arg/N-end rule pathway (eukaryotic)		1.0	14	11	0	(none)	0 of 0	yes
anandamide degradation		1.0	1	1	0	(none)	0 of 0	yes
chondroitin biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
mucin core 1 and core 2 O-glycosylation		1.0	5	5	0	(none)	0 of 0	yes
S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine biosynthesis		1.0	2	2	0	(none)	0 of 0	yes
protein O-[N-acetyl]-glucosylation		1.0	2	2	0	(none)	0 of 0	yes
leukotriene biosynthesis		1.0	6	6	0	(none)	0 of 0	yes
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I		1.0	7	7	0	(none)	1 of 1	yes
4-hydroxy-2-nonenal detoxification		1.0	4	3	0	(none)	0 of 0	yes
gala-series glycosphingolipids biosynthesis		1.0	5	4	0	(none)	0 of 0	yes
15-epi-lipoxin biosynthesis		1.0	5	3	0	(none)	0 of 0	yes
L-tryptophan degradation via tryptamine		1.0	4	4	0	(none)	3 of 3	yes
very long chain fatty acid biosynthesis II		1.0	16	14	0	(none)	0 of 0	yes
inosine 5'-phosphate degradation		1.0	4	4	0	(none)	0 of 0	yes
eumelanin biosynthesis		1.0	6	3	0	(none)	0 of 0	yes
alpha-dystroglycan glycosylation		1.0	7	7	0	(none)	0 of 0	yes
glycogen biosynthesis		1.0	4	4	0	(none)	1 of 1	yes
gamma-linolenate biosynthesis II (animals)		1.0	2	2	0	(none)	1 of 1	yes
inosine-5'-phosphate biosynthesis II		1.0	5	5	0	(none)	1 of 1	yes
zymosterol biosynthesis		1.0	8	8	5	cholesterol biosynthesis I	0 of 0	yes
L-methionine salvage from L-homocysteine		1.0	3	3	0	(none)	0 of 0	yes
human milk oligisaccharides biosynthesis		1.0	19	17	0	(none)	0 of 0	yes
N1-methyl-N3-aminocarboxypropyl-pseudouridine-modified rRNA biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
ceramide de novo biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
taurine biosynthesis I		1.0	3	3	0	(none)	0 of 0	yes
protein citrullination		1.0	1	1	0	(none)	0 of 0	yes
glutaminyl-tRNAgln biosynthesis via transamidation		1.0	4	4	0	(none)	0 of 0	yes
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde		1.0	5	5	0	(none)	0 of 0	yes
vitamin D3 biosynthesis		1.0	4	2	0	(none)	1 of 1	yes
mucin core 3 and core 4 O-glycosylation		1.0	3	3	0	(none)	0 of 0	yes
sphingomyelin metabolism		1.0	3	3	3	sphingolipid biosynthesis (mammals)	0 of 0	yes
ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide		1.0	11	11	2	terminal O-glycans residues modification (via type 2 precursor disaccharide)	0 of 0	yes
fructose 2,6-bisphosphate biosynthesis		1.0	2	2	0	(none)	0 of 0	yes
L-histidine degradation		1.0	6	6	0	(none)	0 of 0	yes
adenosine ribonucleotides de novo biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
homocarnosine biosynthesis		1.0	1	1	0	(none)	0 of 0	yes
myristate biosynthesis (mitochondria)		1.0	25	25	0	(none)	0 of 0	yes
GDP-mannose biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
tetrahydropteridine recycling		1.0	2	2	0	(none)	0 of 0	yes
L-threonine degradation		1.0	2	2	1	2-oxobutanoate degradation I	0 of 0	yes
ultra-long-chain fatty acid biosynthesis		1.0	20	20	0	(none)	0 of 0	yes
epoxysqualene biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
pentose phosphate pathway (oxidative branch) I		1.0	3	3	0	(none)	0 of 0	yes
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)		1.0	5	4	0	(none)	1 of 1	yes
ethanol degradation II		1.0	3	3	0	(none)	1 of 1	yes
allopregnanolone biosynthesis		1.0	2	2	0	(none)	0 of 0	yes
histamine degradation		1.0	3	2	0	(none)	1 of 1	yes
mevalonate pathway I (eukaryotes and bacteria)		1.0	7	7	0	(none)	2 of 2	yes
2-methyl-branched fatty acid beta-oxidation		1.0	14	5	0	(none)	0 of 0	yes
mineralocorticoid biosynthesis		1.0	5	4	0	(none)	0 of 0	yes
2-oxoglutarate decarboxylation to succinyl-CoA		1.0	3	3	0	(none)	1 of 1	yes
5-oxo-L-proline metabolism		1.0	6	4	1	γ-glutamyl cycle	0 of 0	yes
anandamide biosynthesis I		1.0	12	10	0	(none)	3 of 3	yes
glycine betaine degradation II (mammalian)		1.0	4	4	0	(none)	0 of 0	yes
plasmalogen degradation		1.0	8	8	0	(none)	0 of 0	yes
UTP and CTP dephosphorylation I		1.0	7	7	0	(none)	0 of 0	yes
inositol diphosphates biosynthesis		1.0	6	6	0	(none)	0 of 0	yes
formaldehyde oxidation II (glutathione-dependent)		1.0	3	2	0	(none)	1 of 1	yes
NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde		1.0	4	3	0	(none)	0 of 0	yes
thymine degradation		1.0	3	3	0	(none)	0 of 0	yes
glutathione-mediated detoxification I		1.0	8	6	0	(none)	0 of 0	yes
L-citrulline biosynthesis		1.0	8	7	0	(none)	0 of 0	yes
cobalamin salvage (eukaryotic)		1.0	8	7	0	(none)	0 of 0	yes
globo-series glycosphingolipids biosynthesis		1.0	8	8	0	(none)	0 of 0	yes
vitamin K-epoxide cycle		1.0	4	4	0	(none)	0 of 0	yes
histamine biosynthesis		1.0	1	1	0	(none)	0 of 0	yes
pyruvate decarboxylation to acetyl CoA I		1.0	3	3	0	(none)	1 of 1	yes
L-proline biosynthesis		1.0	4	3	0	(none)	0 of 0	yes
L-valine degradation		1.0	8	8	0	(none)	0 of 0	yes
L-asparagine biosynthesis I		1.0	1	1	0	(none)	0 of 0	yes
11-oxyandrogens biosynthesis		1.0	20	19	0	(none)	0 of 0	yes
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis		1.0	4	4	0	(none)	1 of 1	yes
tetrahydrobiopterin de novo biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
5-aminoimidazole ribonucleotide biosynthesis I		1.0	5	5	0	(none)	0 of 0	yes
dolichol and dolichyl phosphate biosynthesis		1.0	6	5	0	(none)	1 of 1	yes
adenine and adenosine salvage III		1.0	4	4	0	(none)	2 of 2	yes
UTP and CTP dephosphorylation II		1.0	3	3	0	(none)	2 of 2	yes
D-myo-inositol-5-phosphate metabolism		1.0	4	4	0	(none)	0 of 0	yes
molybdopterin biosynthesis		1.0	6	5	0	(none)	0 of 0	yes
estradiol biosynthesis II		1.0	3	3	0	(none)	0 of 0	yes
ornithine de novo biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
UTP and CTP de novo biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
androgen biosynthesis		1.0	6	6	0	(none)	0 of 0	yes
UMP biosynthesis I		1.0	6	6	0	(none)	1 of 1	yes
fatty acid biosynthesis initiation (type I)		1.0	3	3	0	(none)	0 of 0	yes
gluconeogenesis		1.0	12	12	0	(none)	0 of 0	yes
glycolysis VI (from fructose)		1.0	11	10	0	(none)	1 of 1	yes
pregnenolone biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
L-isoleucine degradation		1.0	6	6	0	(none)	0 of 0	yes
noradrenaline and adrenaline degradation		1.0	13	13	0	(none)	4 of 4	yes
glucocorticoid biosynthesis		1.0	4	3	0	(none)	0 of 0	yes
thyronamine and iodothyronamine metabolism		1.0	12	8	0	(none)	0 of 0	yes
uroporphyrinogen-III II (from glycine)		1.0	4	4	0	(none)	0 of 0	yes
ketolysis		1.0	3	3	0	(none)	0 of 0	yes
glutathione biosynthesis		1.0	2	2	0	(none)	0 of 0	yes
spermine and spermidine degradation I		1.0	5	5	0	(none)	2 of 2	yes
queuosine biosynthesis II (queuine salvage)		1.0	1	1	0	(none)	0 of 0	yes
myo-inositol biosynthesis		1.0	2	2	0	(none)	1 of 1	yes
lipoate biosynthesis and incorporation V (mammals)		1.0	4	4	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides biosynthesis from CTP		1.0	8	8	0	(none)	1 of 1	yes
L-serine biosynthesis I		1.0	3	3	0	(none)	0 of 0	yes
itaconate biosynthesis I		1.0	2	1	0	(none)	1 of 1	yes
dTMP de novo biosynthesis (mitochondrial)		1.0	3	3	0	(none)	0 of 0	yes
phosphatidylserine biosynthesis I		1.0	1	1	0	(none)	0 of 0	yes
UDP-N-acetyl-D-glucosamine biosynthesis II		1.0	6	6	0	(none)	0 of 0	yes
glycosaminoglycan-protein linkage region biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
heme degradation I		1.0	6	6	0	(none)	0 of 0	yes
L-lysine degradation (saccharopine pathway)		1.0	5	5	0	(none)	0 of 0	yes
oleate biosynthesis		1.0	2	2	0	(none)	0 of 0	yes
ATP biosynthesis		1.0	1	1	0	(none)	0 of 0	yes
L-lysine degradation (pipecolate pathway)		1.0	9	7	0	(none)	0 of 0	yes
CMP phosphorylation		1.0	2	2	0	(none)	0 of 0	yes
ethanol degradation IV		1.0	3	3	0	(none)	1 of 1	yes
NAD salvage pathway IV (from nicotinamide riboside)		1.0	2	2	0	(none)	0 of 0	yes
phospholipases		1.0	5	5	0	(none)	0 of 0	yes
thyroid hormone biosynthesis		1.0	6	5	0	(none)	4 of 4	yes
trans-4-hydroxy-L-proline degradation		1.0	5	4	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides de novo biosynthesis I		1.0	9	9	0	(none)	1 of 1	yes
heparan sulfate biosynthesis		1.0	12	12	0	(none)	0 of 0	yes
i antigen and I antigen biosynthesis		1.0	6	5	5	terminal O-glycans residues modification (via type 2 precursor disaccharide)	0 of 0	yes
ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide		1.0	10	10	0	(none)	0 of 0	yes
procollagen hydroxylation and glycosylation		1.0	6	5	0	(none)	0 of 0	yes
tRNA splicing II		1.0	2	2	0	(none)	1 of 1	yes
protein ubiquitination		1.0	9	9	0	(none)	0 of 0	yes
phosphatidylcholine biosynthesis V		1.0	3	3	0	(none)	0 of 0	yes
ganglio-series glycosphingolipids biosynthesis		1.0	22	22	0	(none)	0 of 0	yes
adenine and adenosine salvage VI		1.0	1	1	0	(none)	0 of 0	yes
protein N-glycosylation initial phase (eukaryotic)		1.0	19	16	0	(none)	0 of 0	yes
pyrimidine ribonucleosides degradation		1.0	2	2	0	(none)	1 of 1	yes
anandamide lipoxygenation		1.0	6	3	0	(none)	0 of 0	yes
lacto-series glycosphingolipids biosynthesis		1.0	7	7	0	(none)	0 of 0	yes
dermatan sulfate biosynthesis		1.0	6	4	0	(none)	0 of 0	yes
protein N-glycosylation processing phase (mammalian)		1.0	20	19	0	(none)	0 of 0	yes
ketogenesis		1.0	5	5	0	(none)	0 of 0	yes
guanosine ribonucleotides de novo biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
phosphatidylcholine biosynthesis I		1.0	3	3	0	(none)	0 of 0	yes
purine ribonucleosides degradation to ribose-1-phosphate		1.0	6	6	0	(none)	0 of 0	yes
neolacto-series glycosphingolipids biosynthesis		1.0	12	12	0	(none)	0 of 0	yes
plasmalogen biosynthesis		1.0	16	15	0	(none)	1 of 1	yes
TCA cycle		1.0	10	10	0	(none)	2 of 2	yes
estradiol biosynthesis I (via estrone)		1.0	4	4	0	(none)	0 of 0	yes
guanosine nucleotides degradation III		1.0	4	4	0	(none)	0 of 0	yes
pyrimidine ribonucleosides salvage I		1.0	3	3	0	(none)	1 of 1	yes
tRNA-uridine 2-thiolation (cytoplasmic)		1.0	8	8	0	(none)	0 of 0	yes
D-myo-inositol (1,3,4)-trisphosphate biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
retinol biosynthesis		1.0	7	7	0	(none)	0 of 0	yes
L-leucine degradation		1.0	6	6	0	(none)	1 of 1	yes
creatine-phosphate biosynthesis		1.0	1	1	0	(none)	0 of 0	yes
D-myo-inositol (1,4,5)-trisphosphate biosynthesis		1.0	5	5	0	(none)	0 of 0	yes
GDP-L-fucose biosynthesis II (from L-fucose)		1.0	2	2	0	(none)	0 of 0	yes
glutathione-peroxide redox reactions		1.0	3	3	1	reactive oxygen species degradation	0 of 0	yes
palmitoyl ethanolamide biosynthesis		1.0	6	3	0	(none)	1 of 1	yes
mitochondrial L-carnitine shuttle		1.0	3	3	0	(none)	1 of 1	yes
stearate biosynthesis		1.0	6	5	0	(none)	1 of 1	yes
protein O-mannosylation II (mammals, core M1 and core M2)		1.0	5	4	0	(none)	0 of 0	yes
thyroid hormone metabolism II (via conjugation and/or degradation)		1.0	14	10	0	(none)	6 of 6	yes
methylglyoxal degradation VIII		1.0	3	3	0	(none)	1 of 1	yes
spermidine biosynthesis I		1.0	2	2	0	(none)	0 of 0	yes
nitric oxide biosynthesis II (mammals)		1.0	3	3	0	(none)	0 of 0	yes
urea cycle		1.0	5	5	0	(none)	2 of 2	yes
uracil degradation I (reductive)		1.0	3	3	0	(none)	0 of 0	yes
sulfide oxidation IV (metazoa)		1.0	5	4	0	(none)	0 of 0	yes
D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis		1.0	4	4	0	(none)	1 of 1	yes
purine deoxyribonucleosides salvage		1.0	6	6	0	(none)	0 of 0	yes
serotonin and melatonin biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
PRPP biosynthesis		1.0	1	1	0	(none)	0 of 0	yes
ubiquinol-10 biosynthesis (late decarboxylation)		1.0	10	8	0	(none)	0 of 0	yes
the visual cycle I (vertebrates)		1.0	12	8	0	(none)	0 of 0	yes
adenosine nucleotides degradation II		1.0	5	5	0	(none)	1 of 1	yes
glycogen degradation II		1.0	6	5	0	(none)	0 of 0	yes
purine deoxyribonucleosides degradation		1.0	3	3	0	(none)	0 of 0	yes
sucrose degradation		1.0	5	5	0	(none)	0 of 0	yes
CMP-N-acetylneuraminate biosynthesis I (eukaryotes)		1.0	5	5	0	(none)	3 of 3	yes
fatty acid beta-oxidation (peroxisome)		1.0	7	7	0	(none)	1 of 1	yes
2-arachidonoylglycerol biosynthesis		1.0	7	6	0	(none)	0 of 0	yes
serotonin degradation		1.0	7	6	0	(none)	1 of 1	yes
hypusine biosynthesis		1.0	5	5	0	(none)	0 of 0	yes
GDP-L-fucose biosynthesis I (from GDP-D-mannose)		1.0	3	3	0	(none)	2 of 2	yes
ophthalmate biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
protein NEDDylation		1.0	3	3	0	(none)	0 of 0	yes
spermine biosynthesis		1.0	2	2	0	(none)	1 of 1	yes
coenzyme A biosynthesis II (eukaryotic)		1.0	4	4	0	(none)	1 of 1	yes
L-selenocysteine biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
tRNA charging		1.0	21	20	0	(none)	0 of 0	yes
retinoate biosynthesis II		1.0	3	3	0	(none)	0 of 0	yes
creatine biosynthesis		1.0	2	2	0	(none)	2 of 2	yes
Rapoport-Luebering glycolytic shunt		1.0	3	3	0	(none)	0 of 0	yes
carnosine biosynthesis		1.0	1	1	0	(none)	0 of 0	yes
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)		1.0	5	5	0	(none)	1 of 1	yes
lanosterol biosynthesis		1.0	1	1	0	(none)	0 of 0	yes
complex N-linked glycan biosynthesis (vertebrates)		1.0	10	10	0	(none)	0 of 0	yes
L-tyrosine degradation		1.0	5	5	0	(none)	0 of 0	yes
phytol degradation		1.0	4	2	0	(none)	1 of 1	yes
hydrogen sulfide biosynthesis II (mammalian)		1.0	6	6	0	(none)	0 of 0	yes
mRNA capping I		1.0	3	3	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotide phosphorylation		1.0	4	4	0	(none)	0 of 0	yes
chondroitin sulfate degradation (metazoa)		1.0	1	1	0	(none)	0 of 0	yes
malonyl-CoA biosynthesis via biotin-carboxyl carrier protein		1.0	4	3	0	(none)	0 of 0	yes

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Please cite the following article in publications resulting from the use of HumanCyc: Genome Biology 6(1):1-17 2004
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