Pathway Listing for Homo sapiens Sorted by Pathway Score

Overview

This page presents some of the evidence used to determine which pathways are present in Homo sapiens. For each pathway, we show

• A diagram (the pathway evidence glyph) summarizing the presence of enzymes for each reaction in the pathway
• The normalized pathway score computed for the pathway
• The total number of reactions in the pathway
• The number of pathway reactions which an enzyme is present in Homo sapiens
• The number of those reactions that appear in other pathways in Homo sapiens (and hence are not unique to the particular pathway)
• The number of reactions designated in MetaCyc as key indicators for the presence of this pathway, for which enzymes are present in Homo sapiens
• Whether this organism is within the taxonomic groups (if any) designated in MetaCyc as the taxonomic range of this pathway

Key to Pathway Evidence Glyph Edge Colors

	Enzyme present. An enzyme for this reaction has been identified in this organism
	Enzyme absent. An enzyme for this reaction has not been identified in this organism
	Unique reaction. This reaction is unique to this pathway in the MetaCyc database
	Enzyme present by hole filler. An enzyme for this reaction has been identified in this organism by the Pathway Hole Filler
	Orphan reaction. No sequenced enzyme from any domain of life is known for this reaction
	Key reaction. The reaction has been designated a key reaction of this pathway
	Spontaneous/other. Used for spontaneous reactions, and for lines that do not denote reactions (e.g., denoting repetition in polymerization pathways)

Pathway Summary Statistics

Fraction of genes devoted to metabolism	3251 of 20979 (15%)
Base pathways	367
Total reactions in the base pathways	1803
Base pathway reactions that are pathway holes	403 (22%)
Base pathway reactions that are not pathway holes	1400 (78%)

Pathways Sorted by Pathway Score

Pathway score is a number between 0 and 1 inclusive that indicates the likelihood that a pathway is present; a higher number indiciates a higher likelihood. The pathway score is not a probability. Pathway scores are computed at pathway prediction time and are not updated later, such as due to editing of a pathway.

A pathway might have no pathway score if its presence was inferred by a curator, or if it is a super-pathway (super-pathways are not scored, and are not included in this page).

Pathways with a score less than the prediction threshold (default=0.15) are typically not predicted as present. An exception to this rule is a case where MetaCyc contains experimental evidence that the pathway exists in the exact organism for which pathway inference was performed, in which case the pathway will be imported from MetaCyc no matter its score.

Pathway	Pathway Glyph	Pathway Score	Total Rxns	Rxns Present in Homo sapiens	Rxns Present in Other Pwys	Other Pwys	Key Rxns Present	In Taxonomic Range?	Links
pyruvate decarboxylation to acetyl CoA		na	3	3	0	(none)	1 of 1	yes
complex N-linked glycan biosynthesis (vertebrates)		na	10	10	0	(none)	0 of 0	yes
globo-series glycosphingolipids biosynthesis		na	8	8	0	(none)	0 of 0	yes
carbon disulfide oxidation III (metazoa)		na	5	1	0	(none)	0 of 0	yes
protein citrullination		na	1	1	0	(none)	0 of 0	yes
glycolysis		na	10	10	0	(none)	0 of 0	yes
retinoate biosynthesis I		na	4	4	0	(none)	0 of 0	yes
phenylethylamine degradation I		na	2	2	0	(none)	1 of 1	yes
GDP-L-fucose biosynthesis II (from L-fucose)		na	2	2	0	(none)	0 of 0	yes
eumelanin biosynthesis		na	6	3	0	(none)	0 of 0	yes
UTP and CTP de novo biosynthesis		na	3	3	0	(none)	0 of 0	yes
plasmalogen degradation		na	8	8	0	(none)	0 of 0	yes
alpha-linolenate metabolites biosynthesis		na	na	na	0	(none)	0 of 0	yes
cardenolide biosynthesis		na	10	1	0	(none)	0 of 0	NO
oxidized GTP and dGTP detoxification		na	4	1	0	(none)	0 of 0	yes
propanoyl CoA degradation I		na	3	3	0	(none)	0 of 0	yes
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis		na	4	4	0	(none)	1 of 1	yes
tetrahydrobiopterin de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
superoxide radicals degradation		na	2	2	2	reactive oxygen species degradation	0 of 0	yes
4-aminobutanoate degradation I		na	2	2	2	GABA shunt	0 of 0	yes
protein O-mannosylation III (mammals, core M3)		na	5	5	0	(none)	0 of 0	yes
spermine biosynthesis		na	2	2	0	(none)	1 of 1	yes
protectin biosynthesis		na	6	4	0	(none)	0 of 0	yes
acetyl-CoA biosynthesis from citrate		na	1	1	0	(none)	0 of 0	yes
lacto-series glycosphingolipids biosynthesis		na	7	7	0	(none)	0 of 0	yes
GDP-L-fucose biosynthesis I (from GDP-D-mannose)		na	3	3	0	(none)	2 of 2	yes
dolichol and dolichyl phosphate biosynthesis		na	6	5	0	(none)	1 of 1	yes
thyronamine and iodothyronamine metabolism		na	12	8	0	(none)	0 of 0	yes
tRNA-uridine 2-thiolation (mammalian mitochondria)		na	4	4	0	(none)	0 of 0	yes
beta-alanine degradation		na	2	2	0	(none)	0 of 0	yes
heme degradation I		na	6	6	0	(none)	0 of 0	yes
NAD salvage		na	2	2	0	(none)	1 of 1	yes
taurine biosynthesis II		na	4	3	0	(none)	0 of 0	yes
C20 prostanoid biosynthesis		na	17	11	0	(none)	0 of 0	yes
icosapentaenoate biosynthesis II (6-desaturase, mammals)		na	7	4	0	(none)	0 of 0	yes
5-oxo-L-proline metabolism		na	6	4	1	γ-glutamyl cycle	0 of 0	yes
histamine biosynthesis		na	1	1	0	(none)	0 of 0	yes
i antigen and I antigen biosynthesis		na	6	5	5	terminal O-glycans residues modification (via type 2 precursor disaccharide)	0 of 0	yes
zymosterol biosynthesis		na	8	8	5	cholesterol biosynthesis I	0 of 0	yes
arachidonate metabolites biosynthesis		na	74	32	0	(none)	0 of 0	yes
neolacto-series glycosphingolipids biosynthesis		na	12	12	0	(none)	0 of 0	yes
epoxysqualene biosynthesis		na	3	3	0	(none)	0 of 0	yes
phosphatidylserine biosynthesis II		na	1	1	0	(none)	0 of 0	yes
L-dopa degradation		na	4	1	0	(none)	1 of 2	yes
retinoate biosynthesis II		na	3	3	0	(none)	0 of 0	yes
acetone degradation III (to propane-1,2-diol)		na	2	2	0	(none)	0 of 0	yes
N1-methyl-N3-aminocarboxypropyl-pseudouridine-modified rRNA biosynthesis		na	3	3	0	(none)	0 of 0	yes
D-myo-inositol (1,4,5)-trisphosphate biosynthesis		na	5	5	0	(none)	0 of 0	yes
bupropion degradation		na	5	1	0	(none)	0 of 0	yes
noradrenaline and adrenaline degradation		na	13	12	0	(none)	3 of 4	yes
pregnenolone biosynthesis		na	3	3	0	(none)	0 of 0	yes
ketolysis		na	3	3	0	(none)	0 of 0	yes
glutamine biosynthesis		na	1	1	0	(none)	0 of 0	yes
dermatan sulfate degradation (metazoa)		na	na	na	0	(none)	0 of 0	yes
molybdenum cofactor biosynthesis		na	3	2	0	(none)	1 of 1	yes
melatonin degradation II		na	4	1	0	(none)	0 of 1	yes
glycine/serine biosynthesis		na	1	1	0	(none)	0 of 0	yes
[2Fe-2S] iron-sulfur cluster biosynthesis		na	10	1	0	(none)	0 of 0	yes
mevalonate pathway		na	7	7	0	(none)	2 of 2	yes
serotonin and melatonin biosynthesis		na	4	4	0	(none)	0 of 0	yes
2'-deoxy-alpha-D-ribose 1-phosphate degradation		na	3	3	0	(none)	0 of 0	yes
ornithine de novo biosynthesis		na	3	3	0	(none)	0 of 0	yes
chondroitin biosynthesis		na	3	3	0	(none)	0 of 0	yes
uracil degradation I (reductive)		na	3	3	0	(none)	0 of 0	yes
pyrimidine ribonucleosides salvage I		na	3	2	0	(none)	1 of 1	yes
NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde		na	4	3	0	(none)	0 of 0	yes
lanosterol biosynthesis		na	1	1	0	(none)	0 of 0	yes
L-cysteine degradation III		na	2	2	0	(none)	0 of 0	yes
L-proline degradation		na	3	2	0	(none)	1 of 1	yes
serotonin degradation		na	7	6	0	(none)	1 of 1	yes
putrescine degradation III		na	4	3	0	(none)	0 of 0	yes
retinol biosynthesis		na	7	7	0	(none)	0 of 0	yes
D-glucuronate degradation		na	5	3	0	(none)	0 of 0	yes
coenzyme A biosynthesis II (eukaryotic)		na	4	4	0	(none)	1 of 1	yes
pyrimidine deoxyribonucleosides degradation		na	3	3	0	(none)	0 of 0	yes
anandamide biosynthesis II		na	8	3	0	(none)	0 of 0	yes
the visual cycle I (vertebrates)		na	12	8	0	(none)	0 of 0	yes
diacylglycerol and triacylglycerol biosynthesis		na	7	4	0	(none)	0 of 0	yes
chondroitin sulfate biosynthesis		na	4	4	0	(none)	0 of 0	yes
geranylgeranyl diphosphate biosynthesis		na	1	1	0	(none)	0 of 0	yes
heme a biosynthesis		na	4	3	0	(none)	2 of 2	yes
trehalose degradation		na	2	2	0	(none)	1 of 1	NO
NAD salvage pathway IV (from nicotinamide riboside)		na	2	2	0	(none)	0 of 0	yes
ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide		na	11	11	2	terminal O-glycans residues modification (via type 2 precursor disaccharide)	0 of 0	yes
progesterone biosynthesis		na	2	2	0	(none)	0 of 0	yes
docosahexaenoate biosynthesis III (6-desaturase, mammals)		na	14	7	0	(none)	0 of 0	yes
itaconate biosynthesis I		na	2	1	0	(none)	1 of 1	yes
N-acetylglucosamine degradation I		na	2	2	0	(none)	0 of 0	yes
D-myo-inositol (1,4,5)-trisphosphate degradation		na	3	3	0	(none)	0 of 0	yes
guanosine ribonucleotides de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
L-asparagine biosynthesis		na	1	1	0	(none)	0 of 0	yes
allopregnanolone biosynthesis		na	2	2	0	(none)	0 of 0	yes
cardiolipin biosynthesis		na	3	3	0	(none)	0 of 0	yes
protein O-mannosylation II (mammals, core M1 and core M2)		na	5	4	0	(none)	0 of 0	yes
L-cysteine biosynthesis III (from L-homocysteine)		na	2	2	0	(none)	0 of 0	yes
glycine biosynthesis		na	1	1	0	(none)	0 of 0	yes
NAD phosphorylation and transhydrogenation		na	2	2	0	(none)	0 of 0	yes
Arg/N-end rule pathway (eukaryotic)		na	14	11	0	(none)	0 of 0	yes
S-methyl-5'-thioadenosine degradation		na	1	1	0	(none)	0 of 0	yes
valproate beta-oxidation		na	9	5	0	(none)	0 of 0	yes
adenosine nucleotides degradation		na	5	5	0	(none)	1 of 1	yes
inositol diphosphates biosynthesis		na	9	9	0	(none)	0 of 0	yes
CMP-N-acetylneuraminate biosynthesis I (eukaryotes)		na	5	5	0	(none)	3 of 3	yes
ganglio-series glycosphingolipids biosynthesis		na	22	22	0	(none)	0 of 0	yes
pyrimidine ribonucleosides degradation		na	2	2	0	(none)	1 of 1	yes
lactose degradation III		na	1	1	0	(none)	0 of 0	yes
palmitoyl ethanolamide biosynthesis		na	6	2	0	(none)	1 of 1	yes
L-glutamate degradation (via 4-aminobutanoate)		na	1	1	1	GABA shunt	0 of 0	yes
trans-4-hydroxy-L-proline degradation		na	5	4	0	(none)	0 of 0	yes
phytol degradation		na	4	2	0	(none)	1 of 1	yes
pentose phosphate pathway (non-oxidative branch)		na	5	5	0	(none)	1 of 1	yes
L-glutamate biosynthesis		na	1	1	1	GABA shunt	0 of 0	yes
L-isoleucine degradation		na	6	6	0	(none)	0 of 0	yes
L-tyrosine degradation		na	5	5	0	(none)	0 of 0	yes
anandamide lipoxygenation		na	6	3	0	(none)	0 of 0	yes
nicotine degradation V		na	18	8	0	(none)	0 of 0	yes
blood coagulation - tissue factor pathway		na	11	8	0	(none)	0 of 0	yes
tetrapyrrole biosynthesis		na	4	4	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation (mitochondria)		na	4	3	0	(none)	1 of 1	yes
L-proline biosynthesis		na	4	3	0	(none)	0 of 0	yes
long-chain fatty acid activation		na	1	1	0	(none)	0 of 0	yes
acyl-CoA hydrolysis		na	1	1	0	(none)	0 of 0	yes
histamine degradation		na	3	2	0	(none)	1 of 1	yes
TCA cycle		na	10	10	0	(none)	2 of 2	yes
flavin biosynthesis		na	2	2	0	(none)	0 of 0	yes
thioredoxin pathway		na	2	1	0	(none)	0 of 0	yes
morphine biosynthesis		na	na	na	0	(none)	0 of 0	yes
2-oxoglutarate decarboxylation to succinyl-CoA		na	3	3	0	(none)	1 of 1	yes
phosphatidylserine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
phosphatidylethanolamine biosynthesis III		na	1	1	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides biosynthesis from CTP		na	8	8	0	(none)	1 of 1	yes
carnosine biosynthesis		na	1	1	0	(none)	0 of 0	yes
melatonin degradation III		na	2	1	0	(none)	0 of 0	yes
putrescine biosynthesis III		na	2	2	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation (animals and fungi, cytoplasm)		na	3	3	0	(none)	0 of 0	yes
L-valine degradation		na	8	8	0	(none)	0 of 0	yes
protein N-glycosylation processing phase (mammalian)		na	20	19	0	(none)	0 of 0	yes
palmitate biosynthesis (cytoplasm)		na	31	1	0	(none)	0 of 0	yes
lipoate salvage		na	na	na	0	(none)	0 of 0	NO
ethanol degradation IV		na	3	3	0	(none)	1 of 1	yes
anthranilate degradation IV (aerobic)		na	na	na	0	(none)	0 of 0	NO
D-mannose degradation		na	1	1	0	(none)	0 of 0	yes
GDP-mannose biosynthesis		na	4	4	0	(none)	0 of 0	yes
adenine and adenosine salvage VI		na	1	1	0	(none)	0 of 0	yes
glutathione-mediated detoxification I		na	8	5	0	(none)	0 of 0	yes
lipoate biosynthesis and incorporation		na	3	3	0	(none)	0 of 0	yes
D-galactose degradation V (Leloir pathway)		na	5	5	0	(none)	0 of 0	yes
UTP and CTP dephosphorylation I		na	7	7	0	(none)	0 of 0	yes
3-phosphoinositide degradation		na	9	8	0	(none)	0 of 0	yes
tRNA-uridine 2-thiolation (cytoplasmic)		na	8	7	0	(none)	0 of 0	yes
ketogenesis		na	5	5	0	(none)	0 of 0	yes
ophthalmate biosynthesis		na	3	3	0	(none)	0 of 0	yes
purine ribonucleosides degradation to ribose-1-phosphate		na	6	6	0	(none)	0 of 0	yes
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)		na	5	5	0	(none)	1 of 1	yes
bile acid biosynthesis, neutral pathway		na	29	19	0	(none)	1 of 1	yes
L-alanine biosynthesis		na	1	1	0	(none)	0 of 0	yes
stearate biosynthesis		na	6	5	0	(none)	1 of 1	yes
glutaminyl-tRNAgln biosynthesis via transamidation		na	4	3	0	(none)	0 of 0	yes
pyridoxal 5'-phosphate salvage		na	5	5	0	(none)	0 of 0	yes
oleate biosynthesis		na	2	2	0	(none)	0 of 0	yes
myo-inositol biosynthesis		na	2	2	0	(none)	1 of 1	yes
sulfite oxidation		na	1	1	0	(none)	0 of 0	yes
melatonin degradation I		na	5	5	0	(none)	2 of 2	yes
ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide		na	10	10	0	(none)	0 of 0	yes
docosahexaenoate biosynthesis IV (4-desaturase, mammals)		na	6	3	0	(none)	1 of 1	yes
L-leucine degradation		na	6	6	0	(none)	1 of 1	yes
L-carnitine biosynthesis		na	4	4	0	(none)	1 of 1	yes
hypusine biosynthesis		na	5	5	0	(none)	0 of 0	yes
glycine betaine degradation II (mammalian)		na	4	3	0	(none)	0 of 0	yes
11-oxyandrogens biosynthesis		na	20	19	0	(none)	0 of 0	yes
methylglyoxal degradation I		na	3	2	0	(none)	1 of 2	yes
alpha-dystroglycan glycosylation		na	7	7	0	(none)	0 of 0	yes
linoleate metabolites biosynthesis		na	14	3	0	(none)	0 of 0	yes
catecholamine biosynthesis		na	4	4	0	(none)	0 of 0	yes
sulfate activation for sulfonation		na	2	2	0	(none)	0 of 0	yes
L-tryptophan degradation via tryptamine		na	4	4	0	(none)	3 of 3	yes
UDP-N-acetyl-D-galactosamine biosynthesis II		na	7	7	0	(none)	1 of 1	NO
GDP-glucose biosynthesis II		na	3	3	0	(none)	0 of 0	yes
sphingosine and sphingosine-1-phosphate metabolism		na	10	6	0	(none)	0 of 0	yes
dTMP de novo biosynthesis (mitochondrial)		na	3	3	0	(none)	0 of 0	yes
arsenic detoxification (mammals)		na	17	8	0	(none)	1 of 3	yes
adenine and adenosine salvage I		na	2	2	0	(none)	0 of 0	yes
L-alanine degradation		na	1	1	0	(none)	0 of 0	yes
acetone degradation I (to methylglyoxal)		na	3	1	0	(none)	0 of 0	yes
MAP kinase cascade		na	4	2	0	(none)	0 of 0	yes
protein N-glycosylation initial phase (eukaryotic)		na	19	16	0	(none)	0 of 0	yes
hydrogen sulfide biosynthesis II (mammalian)		na	6	6	0	(none)	0 of 0	yes
spermine and spermidine degradation I		na	5	5	0	(none)	2 of 2	yes
cobalamin salvage (eukaryotic)		na	8	7	0	(none)	0 of 0	yes
protein ubiquitination		na	9	9	0	(none)	0 of 0	yes
phosphatidylethanolamine biosynthesis II		na	4	3	0	(none)	1 of 1	yes
phospholipases		na	5	5	0	(none)	0 of 0	yes
formaldehyde oxidation II (glutathione-dependent)		na	3	2	0	(none)	1 of 1	yes
androgen biosynthesis		na	6	6	0	(none)	0 of 0	yes
fatty acid alpha-oxidation		na	6	5	0	(none)	2 of 2	yes
L-asparagine degradation I		na	1	1	0	(none)	0 of 0	yes
inosine 5'-phosphate degradation		na	4	4	0	(none)	0 of 0	yes
adenosine deoxyribonucleotides de novo biosynthesis		na	2	2	0	(none)	0 of 0	yes
heme biosynthesis from uroporphyrinogen-III I		na	4	4	0	(none)	1 of 1	yes
fatty acid beta-oxidation		na	7	5	0	(none)	0 of 0	yes
pyruvate fermentation to (S)-lactate		na	1	1	0	(none)	0 of 0	yes
glycosaminoglycan-protein linkage region biosynthesis		na	4	4	0	(none)	0 of 0	yes
methylglyoxal degradation VI		na	4	1	0	(none)	0 of 0	yes
alpha-tocopherol degradation		na	3	1	0	(none)	1 of 1	yes
ubiquinol-10 biosynthesis (late decarboxylation)		na	10	8	0	(none)	0 of 0	yes
Rapoport-Luebering glycolytic shunt		na	3	3	0	(none)	0 of 0	yes
glutathione biosynthesis		na	2	2	0	(none)	0 of 0	yes
ceramide de novo biosynthesis		na	4	4	0	(none)	0 of 0	yes
mitochondrial L-carnitine shuttle		na	3	2	0	(none)	1 of 1	yes
folate transformations I		na	12	9	0	(none)	0 of 0	yes
acyl carrier protein activation		na	1	1	0	(none)	0 of 0	yes
sulfide oxidation IV (metazoa)		na	5	4	0	(none)	0 of 0	yes
vitamin D3 biosynthesis		na	4	2	0	(none)	1 of 1	yes
(S)-reticuline biosynthesis		na	7	1	0	(none)	0 of 0	yes
thyroid hormone biosynthesis		na	6	5	0	(none)	4 of 4	yes
icosapentaenoate biosynthesis III (8-desaturase, mammals)		na	7	4	0	(none)	1 of 1	yes
guanosine nucleotides degradation		na	4	4	0	(none)	0 of 0	yes
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)		na	5	5	0	(none)	1 of 1	NO
L-cysteine degradation I		na	3	2	0	(none)	0 of 0	yes
NADH repair		na	4	4	0	(none)	1 of 1	yes
glycogen biosynthesis		na	4	4	0	(none)	1 of 1	yes
plasmalogen biosynthesis		na	16	15	0	(none)	1 of 1	yes
D-myo-inositol-5-phosphate metabolism		na	4	4	0	(none)	0 of 0	yes
4-hydroxy-2-nonenal detoxification		na	4	4	0	(none)	0 of 0	yes
taurine biosynthesis I		na	3	3	0	(none)	0 of 0	yes
diphthamide biosynthesis		na	3	2	0	(none)	0 of 0	NO
homocarnosine biosynthesis		na	1	1	0	(none)	0 of 0	yes
estradiol biosynthesis II		na	3	3	0	(none)	0 of 0	yes
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate		na	2	2	0	(none)	0 of 0	yes
2-methyl-branched fatty acid beta-oxidation		na	14	8	0	(none)	0 of 0	yes
glycine cleavage		na	3	3	0	(none)	1 of 1	yes
3-phosphoinositide biosynthesis		na	8	8	0	(none)	0 of 0	yes
CDP-diacylglycerol biosynthesis		na	4	3	0	(none)	0 of 0	yes
anandamide biosynthesis I		na	12	9	0	(none)	3 of 3	yes
human milk oligisaccharides biosynthesis		na	19	17	0	(none)	0 of 0	yes
dermatan sulfate biosynthesis		na	6	4	0	(none)	0 of 0	yes
2-arachidonoylglycerol biosynthesis		na	7	6	0	(none)	0 of 0	yes
gluconeogenesis		na	12	12	0	(none)	0 of 0	yes
phosphatidylcholine biosynthesis		na	3	3	0	(none)	0 of 0	yes
L-threonine degradation		na	2	2	1	2-oxobutanoate degradation	0 of 0	yes
adenine and adenosine salvage III		na	4	4	0	(none)	2 of 2	yes
glucocorticoid biosynthesis		na	4	3	0	(none)	0 of 0	yes
molybdopterin biosynthesis		na	6	5	0	(none)	0 of 0	yes
UDP-N-acetyl-D-galactosamine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
L-histidine degradation		na	6	6	0	(none)	0 of 0	yes
L-serine biosynthesis		na	3	3	0	(none)	0 of 0	yes
procollagen hydroxylation and glycosylation		na	6	5	0	(none)	0 of 0	yes
thyroid hormone metabolism II (via conjugation and/or degradation)		na	15	11	0	(none)	6 of 6	yes
thyroid hormone metabolism I (via deiodination)		na	12	9	0	(none)	2 of 2	yes
pyrimidine deoxyribonucleosides salvage		na	5	5	0	(none)	0 of 0	yes
resolvin D biosynthesis		na	11	7	0	(none)	0 of 0	yes
triacylglycerol degradation		na	3	3	0	(none)	1 of 1	yes
chondroitin sulfate degradation (metazoa)		na	1	1	0	(none)	0 of 0	yes
CMP-2-keto-3-deoxy-D-glycero-D-galacto-nononate biosynthesis		na	4	1	0	(none)	0 of 1	yes
fructose 2,6-bisphosphate biosynthesis		na	2	2	0	(none)	0 of 0	yes
BMP Signalling Pathway		na	17	2	0	(none)	0 of 0	yes
thymine degradation		na	3	3	0	(none)	0 of 0	yes
2-oxoisovalerate decarboxylation to isobutanoyl-CoA		na	3	3	0	(none)	1 of 1	yes
nicotine degradation IV		na	16	5	0	(none)	0 of 0	yes
gamma-linolenate biosynthesis		na	2	2	0	(none)	1 of 1	yes
glutathione-peroxide redox reactions		na	3	3	1	reactive oxygen species degradation	0 of 0	yes
sorbitol degradation I		na	3	1	0	(none)	0 of 0	yes
ethanol degradation II		na	3	3	0	(none)	1 of 1	yes
myristate biosynthesis (mitochondria)		na	25	25	0	(none)	0 of 0	yes
queuosine biosynthesis II (queuine salvage)		na	1	1	0	(none)	0 of 0	yes
sphingomyelin metabolism		na	3	3	3	sphingolipid biosynthesis (mammals)	0 of 0	yes
4-hydroxybenzoate biosynthesis		na	5	1	0	(none)	0 of 0	yes
mucin core 3 and core 4 O-glycosylation		na	3	2	0	(none)	0 of 0	yes
protein O-[N-acetyl]-glucosylation		na	2	2	0	(none)	0 of 0	yes
heparan sulfate biosynthesis		na	12	12	0	(none)	0 of 0	yes
glycerol-3-phosphate shuttle		na	2	1	0	(none)	0 of 0	yes
L-serine degradation		na	3	1	0	(none)	0 of 0	yes
guanine and guanosine salvage		na	2	2	0	(none)	0 of 0	yes
L-glutamine degradation		na	1	1	0	(none)	0 of 0	yes
L-lysine degradation (pipecolate pathway)		na	9	7	0	(none)	0 of 0	yes
fatty acid beta-oxidation (unsaturated, odd number)		na	1	1	0	(none)	0 of 0	yes
mRNA capping I		na	3	3	0	(none)	0 of 0	yes
L-methionine degradation		na	3	2	0	(none)	0 of 0	yes
putrescine biosynthesis I		na	2	2	0	(none)	0 of 0	yes
tRNA charging		na	21	20	0	(none)	0 of 0	yes
aspirin triggered resolvin D biosynthesis		na	10	5	0	(none)	0 of 0	yes
di-homo-gamma-linolenate metabolites biosynthesis		na	16	1	0	(none)	0 of 0	yes
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation		na	7	6	0	(none)	1 of 1	yes
icosapentaenoate metabolites biosynthesis		na	35	4	0	(none)	0 of 0	yes
cytochrome c biogenesis		na	1	1	0	(none)	0 of 0	yes
UMP biosynthesis		na	6	6	0	(none)	1 of 1	yes
purine deoxyribonucleosides degradation		na	3	3	0	(none)	0 of 0	yes
malate-aspartate shuttle		na	2	2	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotide phosphorylation		na	4	4	0	(none)	0 of 0	yes
aspirin triggered resolvin E biosynthesis		na	6	4	0	(none)	0 of 0	yes
menaquinol-4 biosynthesis II		na	3	1	0	(none)	0 of 0	yes
D-myo-inositol (1,3,4)-trisphosphate biosynthesis		na	3	3	0	(none)	0 of 0	yes
urea cycle		na	5	5	0	(none)	2 of 2	yes
anandamide degradation		na	1	1	0	(none)	0 of 0	yes
thio-molybdenum cofactor biosynthesis		na	1	1	0	(none)	0 of 0	yes
very long chain fatty acid biosynthesis II		na	16	14	0	(none)	0 of 0	yes
gala-series glycosphingolipids biosynthesis		na	5	4	0	(none)	0 of 0	yes
arachidonate biosynthesis IV (8-detaturase)		na	7	2	0	(none)	0 of 1	yes
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)		na	5	4	0	(none)	1 of 1	yes
acetate conversion to acetyl-CoA		na	1	1	0	(none)	0 of 0	yes
spermidine biosynthesis		na	2	2	0	(none)	0 of 0	yes
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA		na	5	3	0	(none)	0 of 0	yes
lipoxin biosynthesis		na	11	8	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides de novo biosynthesis		na	9	9	0	(none)	1 of 1	yes
L-selenocysteine biosynthesis		na	4	4	0	(none)	0 of 0	yes
purine deoxyribonucleosides salvage		na	6	6	0	(none)	0 of 0	yes
creatine biosynthesis		na	2	2	0	(none)	2 of 2	yes
L-lysine degradation (saccharopine pathway)		na	5	5	0	(none)	0 of 0	yes
erythritol biosynthesis II		na	2	1	0	(none)	0 of 0	yes
ascorbate recycling (cytosolic)		na	6	1	0	(none)	1 of 2	yes
L-aspartate biosynthesis		na	1	1	0	(none)	0 of 0	yes
tetrahydropteridine recycling		na	2	2	0	(none)	0 of 0	yes
glycerol degradation		na	3	1	0	(none)	0 of 0	yes
choline degradation		na	2	2	0	(none)	0 of 0	yes
ultra-long-chain fatty acid biosynthesis		na	20	20	0	(none)	0 of 0	yes
glutaryl-CoA degradation		na	5	5	0	(none)	0 of 0	yes
pentose phosphate pathway (oxidative branch)		na	3	3	0	(none)	0 of 0	yes
vitamin K-epoxide cycle		na	4	4	0	(none)	0 of 0	yes
UDP-N-acetyl-D-glucosamine biosynthesis II		na	6	6	0	(none)	0 of 0	yes
L-phenylalanine degradation I (aerobic)		na	1	1	0	(none)	0 of 0	yes
leukotriene biosynthesis		na	6	6	0	(none)	0 of 0	yes
creatine-phosphate biosynthesis		na	1	1	0	(none)	0 of 0	yes
acylceramide biosynthesis and processing		na	8	7	0	(none)	0 of 0	yes
glycogenolysis		na	6	5	0	(none)	0 of 0	yes
mucin core 1 and core 2 O-glycosylation		na	5	5	0	(none)	0 of 0	yes
biotin-carboxyl carrier protein assembly		na	4	3	0	(none)	0 of 0	yes
aerobic respiration I (cytochrome c)		na	4	4	0	(none)	0 of 0	yes
dopamine degradation		na	5	5	0	(none)	0 of 0	yes
D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis		na	4	4	0	(none)	1 of 1	yes
estradiol biosynthesis I (via estrone)		na	4	4	0	(none)	0 of 0	yes
L-tyrosine biosynthesis		na	1	1	0	(none)	0 of 0	yes
tRNA splicing II		na	2	2	0	(none)	1 of 1	yes
S-adenosyl-L-methionine biosynthesis		na	1	1	0	(none)	0 of 0	NO
UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)		na	1	1	0	(none)	0 of 0	yes
ethanol degradation III		na	3	3	0	(none)	1 of 1	yes
sucrose degradation		na	5	5	0	(none)	0 of 0	yes
fatty acid alpha-oxidation III		na	7	6	0	(none)	1 of 1	yes
thiamine salvage III		na	1	1	0	(none)	0 of 0	yes
guanosine deoxyribonucleotides de novo biosynthesis		na	2	2	0	(none)	0 of 0	yes
folate polyglutamylation		na	5	4	0	(none)	0 of 0	yes
protein S-nitrosylation and denitrosylation		na	5	1	0	(none)	0 of 0	yes
adenosine ribonucleotides de novo biosynthesis		na	3	3	0	(none)	0 of 0	yes
15-epi-lipoxin biosynthesis		na	5	3	0	(none)	0 of 0	yes
L-aspartate degradation I		na	1	1	0	(none)	0 of 0	yes
L-methionine salvage from L-homocysteine		na	3	3	0	(none)	0 of 0	yes
ATP biosynthesis		na	1	1	0	(none)	0 of 0	yes
thiosulfate disproportionation IV (rhodanese)		na	1	1	0	(none)	0 of 0	yes
protein NEDDylation		na	3	3	0	(none)	0 of 0	yes
PRPP biosynthesis		na	1	1	0	(none)	0 of 0	yes
trans, trans-farnesyl diphosphate biosynthesis		na	2	2	0	(none)	1 of 1	yes
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde		na	5	5	5	L-tryptophan degradation XI (mammalian, via kynurenine)	0 of 0	yes
L-dopa and L-dopachrome biosynthesis		na	3	1	0	(none)	0 of 0	yes
arachidonate biosynthesis V (8-detaturase, mammals)		na	6	4	1	arachidonate biosynthesis III (6-desaturase, mammals)	2 of 2	yes
maresin biosynthesis		na	5	3	0	(none)	0 of 0	yes
5-aminoimidazole ribonucleotide biosynthesis		na	5	5	0	(none)	0 of 0	yes
inosine-5'-phosphate biosynthesis		na	5	5	0	(none)	1 of 1	yes
docosahexaenoate metabolites biosynthesis		na	31	16	0	(none)	0 of 0	yes
glutathione-glutaredoxin redox reactions		na	2	1	0	(none)	0 of 0	yes
peptido-conjugates in tissue regeneration biosynthesis		na	17	16	0	(none)	0 of 0	yes
UDP-alpha-D-glucose biosynthesis I		na	2	2	0	(none)	0 of 0	yes
fatty acid beta-oxidation (peroxisome)		na	7	7	0	(none)	1 of 1	yes
methylglyoxal degradation III		na	2	2	0	(none)	0 of 0	yes
enediyne-induced DNA damage		na	na	na	0	(none)	0 of 0	yes
mineralocorticoid biosynthesis		na	5	4	0	(none)	0 of 0	yes
7-(3-amino-3-carboxypropyl)-wyosine biosynthesis		na	4	3	0	(none)	0 of 0	NO
CMP phosphorylation		na	2	2	0	(none)	0 of 0	yes
citrulline-nitric oxide cycle		na	3	3	0	(none)	0 of 0	yes

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Please cite the following article in publications resulting from the use of HumanCyc: Genome Biology 6(1):1-17 2004
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